Hydryllin DM (5/6.25mg) 120ml Syrup
Manufacturer: The Searle Company Limited
Generic Name: Diphenhydramine, Dextromethorphan
Hydryllin DM Syrup combines Dextromethorphan, a cough suppressant that acts on the cough center in the brain, with Diphenhydramine, an antihistamine that helps reduce allergy-related cough and throat irritation. This formulation is designed to provide relief from dry, non-productive cough.
Ingredients
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Diphenhydramine
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Dextromethorphan
Drug Class
Antihistamine + Cough Suppressant
Dosage Form
Syrup / Suspension
Uses
Hydryllin DM Syrup is used for the relief of dry, irritating cough. It helps reduce the frequency of coughing episodes, especially when caused by allergic reactions, throat irritation, or upper respiratory tract infections.
It is not intended for cough associated with smoking, asthma, or emphysema, unless specifically prescribed by a physician.
Dosage
Adults (18 years and above):
1–2 teaspoons, 2–3 times daily, or as directed by a doctor.
Children (below 17 years):
1 teaspoon, 2 times daily.
In Case of Overdose
Symptoms may include excessive drowsiness, confusion, nausea, or vomiting. Immediate medical attention is required.
How to Use
Take by mouth with or without food. Shake well before use. Follow dosage instructions provided by the physician or on the product packaging.
When Not to Use
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Patients with emphysema or chronic cough linked to long-term respiratory disease.
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Hypersensitivity to any of the active ingredients.
Side Effects
Possible side effects include:
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Drowsiness or dizziness
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Nausea or vomiting
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Dry mouth or blurred vision
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Allergic reactions (rash, itching)
Precautions & Warnings
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Use cautiously in patients with asthma, chronic lung disease, heart, liver, or kidney impairment.
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May cause drowsiness — avoid driving or operating heavy machinery after taking.
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Pregnant and breastfeeding women should consult their doctor before use.
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Do not combine with alcohol or other sedating medicines.
Drug Interactions
Inform your doctor of all medications you are using. Interactions may occur with sedatives, alcohol, or other cough/cold preparations.
Storage / Disposal
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Store at room temperature, away from heat, moisture, and direct sunlight.
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Keep out of reach of children and pets.
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Do not use after the expiry date.
Control Drug
No
Doctor’s Review
Dr. Ahsan Ali, Consultant Pulmonologist
“Hydryllin DM Syrup is effective for managing dry, irritating cough that disturbs rest or daily activity. The combination of Dextromethorphan and Diphenhydramine helps reduce cough intensity and throat irritation. It should not be used for chronic cough due to asthma, smoking, or emphysema unless prescribed. Patients should remain cautious about drowsiness, and pregnant or breastfeeding women should only take it after medical advice.”
Disclaimer
This information is provided for educational purposes only. It describes the product and its general medical use in Pakistan. It is not a medical prescription. Always consult a qualified healthcare professional before starting or adjusting any medication.

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