Apodox

Description

Cefpodoxime 200mg Tablet is a third-generation cephalosporin antibiotic that delivers antibacterial activity by disrupting bacterial cell wall synthesis. It targets penicillin-binding proteins (PBPs) crucial for peptidoglycan cross-linking, weakening the cell wall and causing bacterial lysis and death. This action is specific to bacteria, sparing human cells lacking cell walls. It demonstrates broad efficacy against Gram-positive and Gram-negative pathogens, including Streptococcus pneumoniae, Haemophilus influenzae, and Escherichia coli.

Ingredients

• Cefpodoxime 200 mg (per tablet).

Drug Class

• Cephalosporin antibiotic.

Dosage Form

• Tablet

Uses

Cefpodoxime 200mg Tablet is indicated for:

• Treating bacterial infections of the lungs, throat, and urinary tract.
• Managing acute bacterial exacerbations in chronic bronchitis.
• Addressing skin and soft tissue infections from susceptible bacteria.
• Controlling bacterial infection progression and preventing spread.
• Alleviating associated symptoms such as fever, inflammation, and pain.
• Enhancing patient outcomes by reducing or eliminating harmful bacteria.
• Providing effective response to bacterial infections when appropriate.

Dosage

Dosage should always be determined by a doctor’s advice; the following information is provided as supportive reference for informational purposes only.

Adults and Adolescents (12 years and older)

Recommended daily dose: 200 mg to 400 mg. For skin infections, up to 800 mg may be considered.

Infants and Pediatric Patients (2 months to 12 years)

Recommended daily dose: 10 mg/kg.

In Case of Overdose

Overdose may manifest as nausea, vomiting, diarrhea, and abdominal pain. Seek immediate medical assistance for guidance and management to mitigate effects.

Missed Dose

Take the missed dose upon recollection, but skip if nearing the next scheduled dose. Avoid doubling to compensate. For multiple misses, consult a healthcare provider for resumption advice.

How to Use

Swallow the tablet whole with a full glass of water, adhering to prescribed frequency (typically once or twice daily), with or without food as directed.

When Not to Use

Avoid in:

• Known allergies to cefpodoxime or other cephalosporins.
• History of severe penicillin reactions.
• Colitis or severe gastrointestinal disorders.
• Seizures or neurological conditions.
• Severe kidney disease or dialysis.
• Recent stomach surgery or intestinal issues.
• Infants under 3 months.

Side Effects

Possible adverse effects include:

• Diarrhea.
• Nausea and vomiting.
• Abdominal pain.
• Headache.
• Dizziness.
• Skin rash or itching.
• Vaginal yeast infections.
• Fatigue.

Precautions & Warnings

• Not for those allergic to cefpodoxime or cephalosporins.
• Use cautiously in kidney or liver disease; adjustments may be needed.
• Diarrhea may occur; seek care if severe, as it could signal a serious issue.
• Inform provider of gastrointestinal history.
• May reduce oral contraceptive efficacy; use alternatives.
• Elderly: Monitor kidney function due to heightened side effect risk.
• Can cause false positives in some urine glucose tests; use other methods.

Drug Interactions

• Probenecid: May elevate cefpodoxime levels by reducing excretion.
• Nephrotoxic agents (e.g., aminoglycosides): Increased kidney damage risk.
• Other antibiotics (e.g., metronidazole): Potential gut flora changes and resistance.
• Oral contraceptives: Reduced effectiveness; employ backups.
• Aluminum/magnesium antacids: Decreased absorption if concurrent.
• Diuretics: May affect elimination.
• Anticoagulants/antiplatelets: Heightened bleeding risk.

Food Interactions

• Avoid alcohol to prevent amplified side effects like dizziness or stomach upset.
• Grapefruit products: May hinder absorption.
• Dairy: Could reduce absorption; space intake.
• High-fat meals: Might delay absorption; prefer empty stomach or light meal.
• Caffeine: Limit to avoid faster elimination.
• Iron-rich foods: Decrease absorption; time separately.
• Calcium/iron/zinc supplements: Interfere with absorption; take at different times.
• Consult provider for diet-specific advice.

Storage/Disposal

Store at room temperature in a cool, dry place, away from light and moisture, sealed in original container. Avoid bathrooms or heat sources. Do not use expired product; dispose safely without flushing—seek pharmacist guidance. Keep inaccessible to children.

Control Drug

No

Quick Tips

• Follow directed timing, usually twice daily.
• Swallow whole with water; no crushing/chewing.
• Space doses evenly for steady levels.
• If upset occurs, take with food.
• Complete full course regardless of improvement.
• Store away from moisture/sunlight.
• For missed dose: Take soon, unless near next; no doubling.

Doctor’s Review

Dr. Zara Malik (Infectious Disease Specialist): “Cefpodoxime 200mg Tablet serves as a cephalosporin antibiotic that inhibits bacterial cell wall formation by targeting essential proteins, promoting cell lysis, and is effective against a spectrum of pathogens in respiratory, urinary, and skin infections.”

Disclaimer

This product profile is provided for informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. Always consult a qualified healthcare professional before starting, stopping, or changing any medication regimen. The information herein should not be used as a substitute for professional medical guidance.