Praba-2

Glimepiride tablets contain 2 mg of glimepiride, a sulfonylurea that lowers blood sugar by stimulating insulin release from pancreatic beta cells, especially after meals. Used alongside diet and exercise, it helps control type 2 diabetes when metformin alone or with other drugs isn’t enough. It boosts insulin’s effectiveness in the body, maintaining stable glucose levels to reduce risks of heart, kidney, or nerve damage over time. The tablet is taken orally, offering steady control with consistent use.

Primary Uses

• Manages type 2 diabetes (non-insulin-dependent) to control blood sugar levels.

Indications

Used in combination with diet, exercise, and sometimes other antidiabetic drugs (e.g., metformin) for type 2 diabetes when blood sugar is inadequately controlled. Not for type 1 diabetes or diabetic ketoacidosis.

Side Effects

Some may experience low blood sugar (hypoglycaemia), nausea, diarrhea, stomach pain, drowsiness, shakiness, blurred vision, metallic taste, rash, or abnormal vitamin B12 levels. Rarely, liver issues or jaundice may occur. Contact your doctor if severe or persistent.

Warnings

• Pregnancy: Not recommended—may harm the fetus. Consult your doctor.
• Lactation: Avoid; effects on infants unclear. Check with your doctor.
• Driving: Avoid if dizzy or experiencing low blood sugar symptoms.
• Alcohol: Limit or avoid alcohol to prevent worsening low blood sugar.

Precautions

• Use cautiously with liver, kidney, thyroid, or blood disorders.
• Maintain regular meals to avoid hypoglycaemia.
• Inform your doctor about all medications, especially NSAIDs, thyroid drugs, or blood pressure meds (beta-blockers, ACE inhibitors).
• Monitor blood sugar regularly, especially during stress (e.g., illness, surgery).

Contraindications

Avoid if:

• Allergic to glimepiride, sulfonylureas, or sulfonamides.
• You have type 1 diabetes, diabetic ketoacidosis, metabolic/lactic acidosis.
• Malnourished, debilitated, or have adrenal insufficiency, severe lung issues, low oxygen levels, dehydration, or heart failure.

How to Use

Take one tablet by mouth with water, right before or with breakfast (or the first main meal), as prescribed. Swallow whole; don’t crush or chew. Take at the same time daily for consistency. Dosage depends on your condition—follow your doctor’s instructions.

Storage

Store at room temperature (18-25°C), away from light, moisture, and children. Keep in the original packaging.

Quick Tips

• Eat meals on time to prevent low blood sugar.
• Carry a sugar source (e.g., candy) for hypoglycaemia episodes.
• Don’t skip doses or stop without doctor approval.
• Report unusual symptoms like yellowing skin or severe shakiness.

FAQs

How does glimepiride work? It stimulates insulin release from the pancreas and improves insulin action, lowering blood sugar in type 2 diabetes.

Can I take it with other diabetes drugs like sitagliptin? Yes, if prescribed, but monitor meals and doses to avoid low blood sugar. Consult your doctor.

Can I use it with insulin? Yes, if directed by your doctor, but don’t adjust doses yourself to avoid blood sugar swings.

Is it better with metformin? It can be combined with metformin if prescribed, but follow your doctor’s guidance and monitor blood sugar.

Can it cause low blood sugar? Yes, especially if meals are skipped. Eat regularly and carry a sugar source.

Is it safe in pregnancy or breastfeeding? Not recommended; consult your doctor for safer alternatives.

Is it safe with kidney or liver issues? Use cautiously with dose adjustments—consult your doctor.

What if I miss a dose? Take it as soon as you remember unless it’s near the next dose. Don’t double up. Consult your doctor if multiple doses are missed.

Can I use it with a sulfa allergy? No, avoid if allergic to sulfonylureas or sulfonamides.

Can I take it with blood pressure meds? Some may increase hypoglycaemia risk—consult your doctor before combining.

Disclaimer

This information is for general guidance only. Consult a doctor for personalized advice on side effects, precautions, or interactions, as individual needs vary.