Zestril

Description

Zestril Tablets 5mg contain Lisinopril, an ACE inhibitor that lowers blood pressure by blocking the conversion of angiotensin I to angiotensin II—a hormone that causes blood vessels to constrict. By relaxing and widening the blood vessels, Lisinopril helps reduce blood pressure, improve blood flow, and decrease the workload on the heart. It is effective even in patients with low-renin hypertension and is widely used for hypertension, heart failure, and post–heart attack recovery.

Ingredients

Lisinopril 5mg.

Drug Class

ACE Inhibitor (Angiotensin-Converting Enzyme Inhibitor).

Uses

Zestril 5mg is used for:

• Hypertension (High Blood Pressure).

• Heart Failure (Weak Heart Function).

• Post–Myocardial Infarction Management (within 24 hours of heart attack).

• Diabetic Kidney Disease (Nephropathy in Type 2 Diabetics with Hypertension).

Dosage

As prescribed by the physician. Lisinopril 5mg is commonly used as an initial dose but may be adjusted based on blood pressure response and medical condition.

In Case of Overdose

Seek emergency medical attention. Symptoms may include severe dizziness, persistent low blood pressure, or fainting.

Missed Dose

Take as soon as you remember. If it’s near the next dose, skip the missed one. Do not double the dose.

How to Use

Swallow with water, with or without food, preferably at the same time each day.

When Not to Use

Avoid use if you:

• Are allergic to Lisinopril or any ACE inhibitors.

• Have a history of angioedema (swelling of face/lips/throat).

• Are pregnant.

• Have hereditary or idiopathic angioedema.

Side Effects

Common: Dizziness, headache, dry cough, nausea, diarrhea, fatigue
Uncommon: Mood changes, palpitations, abdominal pain, skin rash
Rare: Angioedema, liver dysfunction, kidney problems, electrolyte imbalance

Precautions

Discontinue immediately if swelling of face/lips/tongue occurs. Monitor blood pressure and kidney function regularly.

Warnings

• Warning 1: First doses may cause sudden drop in blood pressure, especially in dehydrated patients or those on diuretics.

• Warning 2: Use with caution in aortic stenosis or left ventricular obstruction.

• Warning 3: May intensify low blood pressure during anesthesia or surgery.

Drug Interactions

May interact with:

• Diuretics.

• Potassium supplements / Potassium-sparing diuretics.

• NSAIDs.

• Lithium.

• Insulin / Oral antidiabetics.

• Nitrates and Antidepressants.

Food Interactions

• Avoid high-salt diets and potassium-rich salt substitutes.

• Limit alcohol intake, as it may enhance dizziness or low blood pressure.

Storage

Store at room temperature, away from heat, moisture, and direct sunlight.

Doctor’s Review — Dr. Imran Siddiqui, Consultant Internal Medicine

“Zestril (Lisinopril) remains one of the most reliable first-line treatments for hypertension and heart failure. Its protective effects on the heart and kidneys make it especially beneficial in diabetic and cardiac patients. However, blood pressure, kidney function, and potassium levels must be monitored regularly.”

Disclaimer

This information is for educational purposes only and should not replace medical advice. Always consult a licensed healthcare provider before using this medication.