Dalacin C 150mg

Dalacin C capsules are a heavy hitter in Pakistani infection units, from surgical wards at Shaukat Khanum in Lahore to ERs at Aga Khan Karachi, where docs deploy them against tough anaerobic or gram-positive bugs in abscesses or post-op sites. As clindamycin HCl, it’s DRAP-approved for serious cases where beta-lactams falter, but C. diff risks keep it reserved. A box of 4 strips (16x150mg capsules) from Pfizer runs about PKR 350-450—stock via Dawaai.pk or Servaid—pulled from hospital logs, prescription locked.

Ingredients

• Active Ingredient: Clindamycin hydrochloride 150mg (equivalent to clindamycin base 137.5mg).
• Excipients: Cornstarch, lactose, talc, magnesium stearate—check for dairy sensitivity.

Drug Class

Lincosamide Antibiotic.

How It Functions

Clindamycin sticks to the 50S ribosomal subunit, blocking bacterial protein synthesis for bacteriostatic (or bactericidal at high doses) effects on gram-positives like Strep and anaerobes like Bacteroides. In Pakistan’s polymicrobial wound infections, it’s hydrolyzed in vivo for quick action, but docs culture to dodge resistance.

Common Applications

Local ID and surgical guidelines hit:

• Serious skin/soft tissue infections or abscesses.
• Respiratory tract infections.
• Gynecological or intra-abdominal infections.
• Bone/joint infections.
• Prophylaxis in contaminated surgeries.

Dosage Form

Capsules taken orally, 150mg every 6 hours, with water.

Potential Side Effects

Up to 1 in 10: Diarrhea, abdominal pain, abnormal LFTs.

Up to 1 in 100: Nausea, vomiting, rash, hives.

Unknown frequency: Vaginal infections, C. diff colitis (fever, bloody stools), blood count drops (eosinophilia, neutropenia), taste changes, esophageal inflammation. ER for severe diarrhea or swelling.

Key Warnings and Precautions

DRAP/PMDC urges:

• GI: High C. diff risk—avoid in colitis history; monitor stool.
• Allergies: Atopic patients cautious; discontinue on rash or anaphylaxis.
• G6PD: With primaquine, watch for hemolysis via blood tests.
• Pregnancy: Category B—consult; breastfeeding okay short-term.
• Liver/Kidney: No adjustment, but monitor in impairment.

Short courses preferred; probiotics for gut shield in desi antibiotics scene.

When It’s Not Suitable (Contraindications)

No if:

• Hypersensitive to clindamycin, lincomycin, or components.

Drug Interactions

Flag:

• Erythromycin—antagonizes effect.
• Neuromuscular blockers—prolongs action.
• Keratolytics or vitamin K antagonists—bleed or skin risks.

In Case of Overdose

GI upset, liver strain—hospital for supportive, no antidote; dialysis minimal help.

Missed Dose

Take ASAP unless near next; skip, no doubles.

Storage and Disposal

Room temp (15-30°C), dry, light/heat-free, kid-proof. Pharmacy drop unused, not trash.

Quick Tips

• With meals if stomach-sensitive.
• Full course to zap bugs.
• Report diarrhea pronto.

Doctor Review

Infectious disease specialists at NICVD or Mayo use Dalacin for anaerobic coverage in diabetic foot ulcers or post-cesarean infections common here, starting 150mg qid with sensitivity checks per DRAP resistance data, but switch off quick to curb C. diff spikes in monsoon guts.

Laboratory Screening

Routine:

• CBC for blood lines, LFTs.
• Stool for C. diff if loose.

This sketches Dalacin C’s anti-bug arsenal in Pakistan—info snapshot, doc’s domain.

Disclaimer: This is product information only, not a prescription or diagnosis. Consult a qualified Pakistani doctor before using Dalacin C capsules to ensure it’s safe. Seek immediate care for severe symptoms like bloody diarrhea, rash, or fever.