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This is a combination medicine containing Doxylamine and Pyridoxine used specifically for pregnant women. It manages nausea and vomiting (morning sickness) when dietary changes or other non-medical approaches don’t work.

Formula

Each tablet contains:

• Doxylamine (antihistamine)
• Pyridoxine (Vitamin B6)

How It Works

Doxylamine blocks histamine, a chemical that triggers nausea and vomiting. Pyridoxine supplements the body with vitamin B6, which is needed for proper fetal growth. Together, they reduce morning sickness while replacing lost nutrients.

What It’s Used For

• Managing nausea and vomiting during pregnancy (morning sickness)
• Can be used in all three trimesters of pregnancy

How to Use

• Take as advised by your doctor.
• Swallow whole with water. Don’t crush or chew.
• Take on an empty stomach.
• Works faster when taken 4-6 hours before eating.
• Don’t stop taking it unless your doctor says so—symptoms may return.
• Continue taking as prescribed even if you feel better.

Important Points

• This medicine manages symptoms for a short period only.
• Cannot completely stop pregnancy-related vomiting.
• May take 5-7 hours to reduce vomiting after taking.
• May need around 2 weeks to show overall improvement.
• Don’t increase the dose without consulting your doctor.

Who Shouldn’t Use It

• People allergic to Doxylamine, Pyridoxine, or other antihistamines (like diphenhydramine)
• Breastfeeding women (passes through breast milk)
• Children and adolescents under 18 years
• Not for non-pregnant individuals

Use With Caution If You Have

• Asthma or lung problems
• Glaucoma
• Stomach ulcers
• Blockage in gut or urinary bladder
• Hyperemesis gravidarum (severe uncontrollable vomiting)
• Upcoming urine test scheduled

Pregnancy and Breastfeeding

• Pregnancy: Safe and intended for pregnant women. Consult your doctor before use.
• Breastfeeding: Not recommended as it passes through breast milk.

Possible Side Effects

Common:

• Feeling sleepy, dizzy, or tired
• Dry mouth

Stop immediately and contact doctor if you experience:

• Allergic reactions (skin rash, itching, swelling of face, lips, mouth, tongue, or throat)
• Difficulty swallowing or breathing

Managing Side Effects

Dizziness or drowsiness:

• Rest and get enough sleep
• Avoid driving or operating machinery
• Don’t consume alcohol—it worsens dizziness
• Consult your doctor if condition doesn’t improve

Precautions

• May cause dizziness or drowsiness—be careful while driving or handling heavy machinery.
• Avoid alcohol during treatment.
• Store at room temperature, out of reach of children.

Drug Interactions

Inform your doctor if you’re taking:

• Antibiotics (linezolid)
• Parkinson’s disease medicines (levodopa)
• Methylene blue (blood disorder medicine)
• Bladder or bowel medicines (solifenacin, scopolamine)
• Antidepressants (sertraline, citalopram)
• Anti-anxiety medicines (alprazolam, lorazepam)
• Allergy medicines (cetirizine, fexofenadine)
• Anesthetics (etomidate, sevoflurane)
• Pain relievers (fentanyl, codeine, paracetamol, ibuprofen)
• Cough medicine (dextromethorphan)
• Vitamin B supplements

Food Interactions

Avoid taking with food—it delays absorption.

Overdose Signs

Restlessness, dry mouth, dilated pupils, blurred vision, dizziness, extreme sleepiness, spinning sensation, confusion, increased heartbeat, seizures, severe muscle pain or weakness. Get immediate medical help.

Missed Dose

Take when you remember. If next dose is near, skip the missed one. Don’t double up.

Common Questions

Does it affect fetal growth? No. It’s generally safe and doesn’t affect the baby’s development.

Is it addictive? No, it doesn’t cause addiction.

Can I use it without consulting a doctor? No. Always consult your doctor first, especially if you have asthma, stomach problems, or glaucoma.

Can I give it to my child? No. Not intended for children.

Can I stop once symptoms improve? No. Continue as prescribed—symptoms may return if stopped suddenly.

Disclaimer: This information is for educational purposes only and is not a medical prescription. Always consult your doctor before taking this medicine, especially regarding your specific health condition, proper dosage, and duration of treatment.