Gravibinan 2ml

Gravibinan injection contains hydroxyprogesterone caproate, a synthetic form of the hormone progesterone. Progesterone is naturally produced in the female body and is important in maintaining pregnancy. This injection is commonly prescribed to support pregnancy in women who are at risk of miscarriage or premature labor. It works by strengthening the lining of the uterus and helping it hold the pregnancy.

Primary Uses

• To prevent threatened miscarriage

• To support pregnancy in women with a history of repeated miscarriages

• To reduce the risk of premature labor in selected cases

How to Use

• Administered as an intramuscular injection (into the muscle) by a healthcare professional.

• Dosage and frequency are decided by the treating gynecologist.

• Do not self-inject. Always follow your doctor’s instructions.

Side Effects

Some women may experience:

• Pain, redness, or swelling at the injection site

• Headache

• Nausea or vomiting

• Breast tenderness

• Mood changes

• Drowsiness

Less common but serious side effects include:

• Allergic reaction (rash, itching, swelling of face or lips, difficulty breathing)

• Blood clots (pain, swelling in legs, chest pain, shortness of breath)

• Liver problems (yellowing of eyes/skin, dark urine)

Seek medical advice immediately if any severe side effects occur.

Warnings & Precautions

• Not recommended if you have unexplained vaginal bleeding, severe liver disease, or history of blood clots.

• Use only if clearly needed during pregnancy and under close medical supervision.

• Inform your doctor if you have diabetes, high blood pressure, epilepsy, asthma, or migraine.

• Avoid alcohol and smoking during treatment, as they can increase pregnancy risks.

Contraindications

Do not use Gravibinan if you have:

• Allergy to progesterone or any component of the injection

• History of blood clots (deep vein thrombosis, pulmonary embolism)

• Severe liver impairment or liver tumors

• Known or suspected breast or reproductive system cancer

Doctor’s Review – Dr. Ayesha Malik, Consultant Gynecologist & Obstetrician:
Gravibinan is used as supportive therapy for women at risk of pregnancy loss or premature delivery, but it must always be given at the right time under strict medical supervision.

FAQs

Is Gravibinan safe during pregnancy?
Yes, but only under a doctor’s prescription. It is used to support pregnancy in high-risk cases.

How is it given?
It is given as a deep intramuscular injection by a nurse or doctor.

Can it be used while breastfeeding?
It is generally not recommended during breastfeeding unless your doctor advises otherwise.

What if I miss a scheduled dose?
Inform your doctor. Do not double the dose without medical advice.

Storage

• Store at room temperature (below 25°C).

• Protect from direct light and heat.

• Keep out of reach of children.

Disclaimer

This information is for educational purposes only and is not a prescription. Gravibinan should be used strictly under the supervision of a qualified doctor. Always consult your gynecologist before starting or stopping this treatment.