Afloxan 300 mg tablets contain ofloxacin, a broad-spectrum fluoroquinolone antibiotic used to treat various bacterial infections. Ofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA replication and transcription, thereby leading to bacterial cell death.
Key Features:
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Active Ingredient: The active component of Afloxan is ofloxacin, which has a wide range of activity against both Gram-positive and Gram-negative bacteria.
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Indications: Afloxan 300 mg is prescribed for the treatment of several types of infections, including:
- Urinary Tract Infections (UTIs): such as cystitis and pyelonephritis.
- Respiratory Tract Infections: including bronchitis and pneumonia.
- Skin and Soft Tissue Infections.
- Sexually Transmitted Infections (STIs): such as gonorrhea.
- Certain gastrointestinal infections.
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Mechanism of Action: Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes necessary for DNA replication and repair. By disrupting these processes, it prevents the bacteria from multiplying and ultimately leads to their death.
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Dosage and Administration: Afloxan 300 mg tablets are typically taken orally, with or without food. The usual dosage is one tablet once or twice daily, depending on the type and severity of the infection. It’s important to follow the prescribed dosage and complete the full course of treatment to ensure the infection is fully eradicated.
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Side Effects: Common side effects may include nausea, diarrhea, headache, dizziness, and abdominal pain. Serious side effects, though less common, can include tendonitis or tendon rupture, especially in older adults or those on corticosteroids, as well as potential central nervous system effects such as seizures or hallucinations.
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Precautions: Before taking Afloxan, patients should inform their healthcare provider of any history of tendon disorders, seizure disorders, or other medical conditions. It is also important to avoid excessive sun exposure while taking this medication, as it can increase sensitivity to sunlight.
Afloxan 300 mg tablets are an effective option for treating a variety of bacterial infections. Proper adherence to the prescribed regimen and monitoring for potential side effects are essential for achieving the best therapeutic outcomes.
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