Amsipol

Primary Uses

• Relief of mild to moderate pain: headaches, menstrual cramps, toothaches, backaches, osteoarthritis, muscle aches

• Fever reduction

• Improves mental alertness (due to caffeine component)

Indications

• Pain associated with tension headaches, dysmenorrhea, non-articular rheumatism

• Fever due to cold, flu, or viral infection

• Combination use: Caffeine enhances paracetamol’s effect and may help with migraine relief

How to Use

• Take orally with water

• Swallow tablets whole; do not crush, chew, or split

• Can be taken with or without food

• Follow dosage instructions from your doctor; do not exceed recommended doses

• Maintain regular intervals for optimal effect

Precautions

• Pregnancy: Generally safe but consult your doctor

• Lactation: Minimal risk; consult healthcare provider

• Driving / Mental Alertness: May cause drowsiness; caffeine may increase alertness

• Alcohol: Limit or avoid alcohol

• Liver/Kidney Disease: Consult doctor before use

• Serious Skin Reactions: Discontinue immediately if rash, itching, swelling occurs

• Other Conditions: Exercise caution in patients with heart disease, CNS disorders, anxiety/depression, bleeding disorders

Side Effects

• Generally well tolerated

• Possible: restlessness, insomnia, allergic reactions (rare)

• Seek immediate medical attention if rash, swelling, or breathing difficulty occurs

Contraindications

• Severe heart impairment

• Severe kidney or liver impairment

• Malnutrition or dehydration

• Alcoholism or heavy alcohol use

• Weight <50 kg

• Severe anemia

Overdose / Emergency Signs

• Difficulty breathing

• Loss of consciousness

• Seek emergency care immediately

Storage

• Store at room temperature (18–25°C)

• Keep away from moisture, light, and children

Mechanism of Action

• Paracetamol: Blocks pain signals in the brain; reduces fever

• Caffeine: Stimulates the central nervous system, enhances analgesic effect, increases alertness

Additional Notes

• Not recommended for long-term use (>3 days) without medical supervision

• Drink plenty of water to prevent dehydration

• Avoid doubling doses if a dose is missed