Artecxin Forte 40 mg / 240 mg Tablet

Brand: Highnoon
Generic Name: Artemether + Lumefantrine

Composition

• Artemether 40 mg – Rapidly acting antimalarial

• Lumefantrine 240 mg – Longer-acting antimalarial to prevent recurrence

Artecxin Forte is a combination antimalarial medication used for the treatment of severe malaria, including cerebral malaria, and as a second-line therapy for chloroquine-resistant Plasmodium falciparum malaria. Artemether acts quickly to reduce parasite load, while lumefantrine ensures sustained antimalarial activity to prevent relapse.

Primary Uses

• Treatment of severe malaria, including cerebral malaria

• Second-line treatment for chloroquine-resistant falciparum malaria

How to Use

• Take as prescribed by your doctor.

• Usually taken orally in multiple doses over three days, depending on severity.

• Do not skip doses and complete the full course.

• Avoid alcohol during treatment.

Side Effects

• Abdominal pain.

• Anorexia (loss of appetite).

• Diarrhea, nausea, vomiting.

• Dizziness.

• Reticulocytopenia (reduced immature red blood cells).

• Rare cardiac complications (arrhythmias).

If side effects persist or worsen, seek medical attention immediately.

Warnings & Precautions

Pregnancy & Lactation:

• Contraindicated during pregnancy.

• Avoid during lactation; may harm the baby.

Heart and Electrolytes:

• Caution in patients with electrolyte disturbances, arrhythmias, bradycardia, congestive heart failure, or a family history of sudden cardiac death.

• Avoid use with other drugs that prolong QT interval.

Other Precautions:

• Use caution in renal or severe cardiac impairment.

• Avoid activities requiring alertness (e.g., driving) if dizziness or drowsiness occurs.

Drug Interactions

• CYP3A4 inhibitors.

• CYP2D6 substrates.

• Antiarrhythmics (Class Ia, III).

• Antidepressants, antipsychotics.

• Hormonal contraceptives.

• Azole antifungals.

• Grapefruit juice.

Contraindications

• History of arrhythmias, bradycardia, or congestive heart failure

• Severe electrolyte disturbances

Storage

• Store at room temperature (18–25°C).

• Keep away from excessive light, moisture, and children.

• Do not flush unused medicine. Follow local disposal guidelines.

FAQS

1. Can Artecxin Forte prevent malaria?

• No, this medicine is for treatment only, not prevention.

2. How is it administered?

• Typically orally as a multi-dose regimen; intravenous use may be used in severe cases under medical supervision.

3. Is it safe for diabetics?

• Caution is advised; inform your doctor about existing conditions or medications.

4. Can it be used during pregnancy or breastfeeding?

• Avoid unless clearly needed and prescribed by a healthcare provider.

Doctor Review

Dr. Ayesha Khan, MBBS, Infectious Diseases
“Artecxin Forte is highly effective for severe malaria caused by resistant strains. It should be used under strict medical supervision due to potential cardiac risks. Completing the full course is critical to prevent relapse.”

Disclaimer

The information here is for educational purposes only. Do not use it as a substitute for professional medical advice. Always consult a qualified healthcare provider regarding dosage, interactions, or medical conditions.