Arynoin

Arynoin (Isotretinoin) is a systemic retinoid medicine used for the treatment of severe acne that does not respond to standard therapies such as antibiotics or topical treatments. It works by reducing sebaceous gland activity, keratinization, and inflammation, helping to prevent scarring and long-term skin damage. Because of its potency and risk profile, Isotretinoin is always prescribed under strict medical supervision.

Uses

• Treatment of severe, resistant acne.

• Reduces excess oil (sebum) production.

• Prevents acne-related scarring.

• Helps treat nodular and cystic acne.

Dosage

• Dosage is individualized and must be prescribed by a dermatologist.

• Taken once or twice daily with meals.

• Swallow the capsule whole with water — do not crush or chew.

• Continue use as advised, typically for 15–20 weeks (duration varies).

How to Use

• Take with food for better absorption.

• Swallow whole with a full glass of water.

• Take at the same time daily for consistency.

• Do not share with others, even if symptoms are similar.

In Case of Overdose

Seek emergency medical help. Symptoms may include headache, dizziness, vomiting, loss of balance, dry or cracked lips, and tingling sensations.

Missed Dose

• Skip the missed dose if it is almost time for your next scheduled dose.

• Do not double doses to make up for the missed one.

When Not to Use

• Pregnancy or if planning to conceive — may cause serious birth defects.

• During breastfeeding.

• In individuals with liver disease or high blood lipid levels (unless closely monitored by a doctor).

• In patients with a history of severe depression or psychiatric illness without medical supervision.

Side Effects

Common side effects:

• Dry skin, lips, and eyes.

• Cold/flu-like symptoms.

• Headaches.

Serious side effects (seek medical help):

• Vision or hearing problems (including ringing in ears).

• Severe gastrointestinal pain or bleeding.

• Joint or muscle pain.

• Frequent urination or kidney issues.

• Mood changes or depression.

Precautions & Warnings

• Women must avoid pregnancy during treatment and at least 1 month after stopping.

• Do not donate blood while on isotretinoin or within 30 days of stopping.

• Avoid cosmetic skin procedures (laser, waxing, dermabrasion) during treatment.

• Regular blood tests may be required to monitor liver function and cholesterol levels.

• Inform your doctor about any history of psychiatric illness, liver disease, or high cholesterol.

Drug Interactions

Consult your doctor if you are using:

• Phenytoin (for seizures).

• Birth-control pills.

• NSAIDs (painkillers like ibuprofen).

• Corticosteroids.

• Multivitamins with Vitamin A (risk of toxicity).

• Tetracycline antibiotics (e.g., doxycycline).

Storage/Disposal

• Store at room temperature, away from heat, moisture, and direct sunlight.

• Keep out of reach of children.

• Do not share unused capsules — dispose of safely according to pharmacist advice.

Quick Tips

• Take with meals for best absorption.

• Use a moisturizer and lip balm regularly to manage dryness.

• Avoid alcohol to reduce liver strain.

• Always use effective birth control during and after treatment as advised.

• Regularly attend follow-up appointments for monitoring.

Doctor’s Review

“Isotretinoin is a breakthrough treatment for severe, resistant acne. It works by controlling excess oil production and reducing the risk of permanent scarring. However, due to its potential risks, including effects on pregnancy and mood. Patients should never use this medicine without professional supervision.”
— Prof. Dr. Saima Malik, MBBS, FCPS

Disclaimer

This information is provided for educational and product knowledge purposes only.
It is not a medical prescription. Always consult a qualified dermatologist or healthcare professional before starting, changing, or stopping Arynoin (Isotretinoin).