Clefer 100mg

Clefer Injection (Iron Sucrose USP) is an intravenous iron replacement therapy containing a complex of polynuclear iron(III)-hydroxide bound to sucrose. It is formulated as a sterile brown aqueous solution for controlled delivery of elemental iron to restore iron levels in patients with iron deficiency.

Functions / Therapeutic Use

• Replenishes iron stores in iron deficiency anemia.

• Used when rapid iron supplementation is required.

• Suitable for patients who cannot tolerate or do not respond to oral iron.

• Beneficial in chronic kidney disease, inflammatory bowel disease, or cases of impaired iron absorption.

Ingredients

• Active: Iron Sucrose (20 mg elemental iron per ml).

• Excipients: Water for injection and stabilizers.

Warnings

• Risk of hypersensitivity or anaphylactoid reactions; monitor patients for at least 30 minutes post-injection.

• Use with caution in patients with liver dysfunction or acute infection.

• Avoid in first trimester of pregnancy unless clearly necessary.

• Must be administered by trained professionals with resuscitation facilities available.

Adverse Effects

• Common: Hypotension, nausea, taste disturbances.

• Uncommon: Headache, dizziness, flushing, abdominal discomfort.

• Rare / Serious: Anaphylaxis, bronchospasm, angioedema, syncope.

Cautions

• Do not administer intramuscularly.

• Avoid simultaneous oral iron therapy (start oral iron ≥5 days after last dose).

• Prevent paravenous leakage to avoid skin discoloration.

• Monitor iron parameters to prevent overload.

Reviewed by Dr. Ayesha Rahman (MBBS, Hematology Specialist)

Disclaimer: This information is intended for general reference only and is not a substitute for professional medical advice. Always consult a qualified healthcare provider before initiating or modifying any treatment.