Dasavir

Description
Dasavir tablets contain Daclatasvir, an oral antiviral medication used in combination with other drugs for the treatment of chronic Hepatitis C infection. It works by inhibiting the NS5A protein of the Hepatitis C virus (HCV), which is essential for viral replication and assembly. By blocking this protein, Dasavir helps reduce viral load and promotes liver recovery. It is not used alone and must be taken as part of a combination therapy, typically with Sofosbuvir or other direct-acting antivirals (DAAs).

Ingredients

• Daclatasvir Dihydrochloride 30mg (per 30mg tablet).

• Daclatasvir Dihydrochloride 60mg (per 60mg tablet).

Drug Class
Antiviral / Hepatitis C Treatment (NS5A Inhibitor).

Uses
Doctors prescribe Dasavir for:

• Treatment of chronic Hepatitis C virus (HCV) infection.

• Used in combination with Sofosbuvir or Ribavirin, depending on genotype.

• Helps achieve Sustained Virologic Response (SVR)—a functional cure of Hepatitis C.

Doctor’s Review
Hepatology specialists highlight that “Daclatasvir-based regimens significantly improve cure rates in Hepatitis C patients when used as directed in combination therapy. Patient adherence is key to successful viral clearance.”

Dosage (as part of combination therapy, as directed by physician).

• Adults:

  • 60mg once daily (standard dose), taken with Sofosbuvir 400mg.

  • 30mg dose may be used if given with certain interacting medications.

• Treatment duration is typically 12 to 24 weeks, depending on HCV genotype and liver condition.

• Never use Dasavir alone — always part of a prescribed combination.

In Case of Overdose
May cause fatigue, headache, nausea, or abnormal liver function tests. Seek immediate medical attention. Symptomatic and supportive care is advised.

Missed Dose
Take as soon as remembered unless it is close to the next scheduled dose. Do not double up. Continue regular dosing routine.

How to Use

• Swallow whole with water, with or without food.

• Take at the same time each day.

• Do not skip or stop treatment early, as viral resistance may develop.

When Not to Use

Do not use Dasavir if:

• Allergic to Daclatasvir or any excipient.

• Taking contraindicated interacting drugs (e.g. strong CYP3A inducers like Rifampicin or Phenytoin).

• Pregnant or breastfeeding, unless advised by a physician.

• Severe cardiac or liver impairment without close monitoring.

Side Effects

Common side effects (usually mild):

• Headache.

• Fatigue or tiredness.

• Nausea or stomach discomfort.

• Insomnia.

• Possible elevated liver enzymes when combined with other antivirals.

Precautions & Warnings

• Regular liver function monitoring is advised.

• Use in combination only — monotherapy is ineffective.

• Inform doctor of existing liver or kidney disease.

• Avoid alcohol or hepatotoxic substances during treatment.

Drug Interactions

• Avoid with Rifampicin, Phenytoin, Carbamazepine, St. John’s Wort — may reduce effectiveness.

• May interact with antiretrovirals, anticonvulsants, and blood thinners — dose adjustments required.

Food Interactions

• Can be taken with or without food.

• Avoid alcohol to protect the liver during antiviral therapy.

Storage/Disposal

• Store below 25°C in original packaging.

• Protect from heat, moisture, and direct sunlight.

• Dispose of unused tablets safely as per medical guidelines.

Quick Tips

• Always pair with Sofosbuvir or other prescribed antivirals — never use alone.

• Adherence is crucial — missing doses may reduce treatment success.

• Avoid alcohol throughout the treatment cycle.

• Schedule regular liver function tests.

Disclaimer
This information is for educational purposes only and does not replace professional medical advice. Always consult a qualified healthcare provider before starting or adjusting any Hepatitis C treatment. To be sold only on prescription.