Divestra 2mg/35mcg Tablet (21’s)

Brand: Aspin Pharma
Generic Name: Cyproterone acetate (2mg) + Ethinylestradiol (35mcg)
Drug Class: Sex Hormones (Anti-androgen + Estrogen)
Form: Tablet
Pack Size: 21 tablets
Prescription: Required

Overview

Divestra is a hormonal combination medicine containing Cyproterone acetate and Ethinylestradiol. It is primarily prescribed to treat polycystic ovary syndrome (PCOS) symptoms, such as severe acne, irregular periods, and excessive hair growth, caused by the overproduction of male hormones (androgens).
In addition, Divestra also has contraceptive properties, so women taking it for PCOS or acne management usually do not need another birth control pill. However, it is not recommended solely as a contraceptive unless other symptoms are also present.

Key Features

• Combination of anti-androgen (Cyproterone) and estrogen (Ethinylestradiol).

• Reduces androgen (male hormone) effects in females.

• Effective in treating severe acne and PCOS-related symptoms.

• Provides contraceptive protection during use.

• Each pack contains 21 tablets.

Uses of Divestra

Divestra is prescribed for:

• Severe acne not responding to antibiotics or standard treatments.

• Excessive hair growth (hirsutism) due to high androgen levels.

• Irregular menstrual cycles associated with PCOS.

• Seborrhea (oily skin/scalp condition).

• Dual benefit of contraception while treating hormonal imbalance.

How to Use

• Take 1 tablet daily for 21 days, starting from the first day of the menstrual cycle.

• Swallow with a full glass of water, with or without food.

• After finishing 21 tablets, take a 7-day break (during which withdrawal bleeding occurs), then restart a new pack.

• Take at the same time every day to ensure effectiveness.

• Do not skip doses — missing pills may reduce contraceptive protection.

Dosage

• As prescribed by your doctor, usually one tablet per day for 21 consecutive days, followed by 7 pill-free days.

• Treatment may continue for several cycles, depending on your condition.

When Not to Use

Avoid Divestra if you:

• Are pregnant or breastfeeding

• Have a history of blood clots, stroke, or circulation disorders

• Have liver disease, jaundice, or liver tumors

• Suffer from uncontrolled high blood pressure

• Have hormone-related cancers (e.g., breast or endometrial cancer)

• Experience severe migraine headaches

Side Effects

Some women may experience:

• Headache, nausea, abdominal pain

• Breast tenderness or discomfort

• Mood swings, depression

• Weight gain or bloating

• Changes in menstrual bleeding pattern

Seek urgent medical attention if you develop chest pain, sudden vision changes, shortness of breath, or leg swelling (possible signs of blood clot).

Precautions & Warnings

• Inform your doctor about any history of circulatory disorders, liver impairment, jaundice, gallstones, or systemic diseases (like lupus, porphyria, or Sydenham’s chorea).

• Regular medical checkups may be required during long-term use.

• Not suitable for women after menopause.

• Not recommended for men.

• Avoid smoking and excessive alcohol while on this medicine, as they increase side effects and clotting risk.

Drug Interactions

Some medicines may reduce the effect of Divestra, including:

• Certain antibiotics (e.g., penicillin, tetracyclines)

• Antiepileptics (e.g., phenytoin, carbamazepine)

• Medicines for tuberculosis (e.g., rifampicin)

• Herbal remedies like St. John’s Wort

Always inform your doctor about all medicines, supplements, or herbal products you are taking.

Overdose Symptoms

Taking more than the prescribed dose may cause:

• Nausea and vomiting

• Vaginal bleeding

Seek immediate medical advice in case of overdose.

Storage

• Store at room temperature (below 25°C), away from heat, sunlight, and moisture.

• Keep out of reach of children.

• Do not use expired tablets.

FAQs

Q. Can teenagers use Divestra?
Yes, but only after the onset of menstruation (menarche), typically between ages 10–16.

Q. Can I use Divestra after menopause?
No, it is not recommended after menopause.

Q. Can males use this medicine for acne?
No, this medicine is strictly for females only.

Q. What if I forget a dose?
Take it as soon as you remember. If it’s close to your next dose, skip the missed one. Do not double the dose.

Disclaimer

This information is provided for educational purposes only and should not replace advice from a qualified healthcare provider. Always consult your doctor before starting, stopping, or changing any medication.

Medical Review by Dr. Dhivya Selvaraj