Donresp contains Risperidone, an atypical antipsychotic medicine. It works by balancing dopamine and serotonin activity in the brain. This helps reduce hallucinations, disorganized thinking, mood swings, and irritability. In Pakistan, Donresp is prescribed under psychiatric supervision for managing schizophrenia, bipolar disorder, and behavioral symptoms in autism.
Primary Uses
Donresp is used in the management of:
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Schizophrenia – reducing hallucinations, paranoia, and disorganized thought.
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Bipolar disorder – stabilizing mood and controlling manic episodes.
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Irritability linked to autism – managing aggression, mood swings, and self-injury in children/adolescents.
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Behavioral disturbances in dementia. (restricted use, under specialist care)
Side Effects
Possible side effects include:
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Sleepiness or dizziness.
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Weight gain and increased appetite.
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Headaches.
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Stiffness or tremors.
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Restlessness or difficulty moving.
Less common but serious effects:
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Stroke risk in elderly patients with dementia.
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Elevated blood sugar or cholesterol.
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Rare cardiac rhythm disturbances. (QT prolongation)
Precautions & Warnings
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Not suitable for elderly patients with dementia, due to increased stroke risk.
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Use with caution in individuals with diabetes, high cholesterol, or heart disease.
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Avoid overheating and dehydration, as this may worsen side effects.
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Should not be combined with sedatives or alcohol, as these may intensify drowsiness.
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Pregnant or breastfeeding women should only use under medical guidance.
Contraindications
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Known allergy to Risperidone.
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Severe cardiovascular disorders.
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Use in elderly patients with dementia-related psychosis.
Drug Interactions
Donresp may interact with:
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Anti-anxiety medicines. (increased sedation risk)
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Antihistamines. (enhanced drowsiness)
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Medicines that affect heart rhythm or blood pressure.
Storage & Handling
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Store at room temperature (below 30°C), away from heat and moisture.
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Protect from direct sunlight.
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Keep out of reach of children.
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Do not use after expiry date.
FAQs
Q: What is Donresp 3mg mainly used for?
A: It is used for treating schizophrenia, bipolar disorder, and irritability in autism.
Q: Can I take Donresp without food?
A: Yes, it can be taken with or without food, but many patients take it after meals to reduce stomach upset.
Q: Is it safe for elderly patients?
A: It should not be used in elderly patients with dementia due to stroke risk.
Q: Does it cause drowsiness?
A: Yes, drowsiness and sleepiness are common side effects.
Doctor’s Review
Dr. Ayesha Malik, MBBS, FCPS – Psychiatry
“Donresp (Risperidone) is an antipsychotic medicine used in managing conditions such as schizophrenia and bipolar disorder, where it can help reduce hallucinations, aggression, and mood instability. It is also prescribed in selected cases of autism to address irritability and behavioral challenges. While effective in stabilizing symptoms, it requires careful monitoring for side effects, including weight changes, drowsiness, and movement-related issues. Use in elderly patients with dementia is generally avoided due to associated stroke risks. With appropriate supervision, Donresp serves as a dependable option for complex psychiatric care.”
Disclaimer
This information is provided for educational and product awareness purposes only. It is not a medical prescription. Always consult a qualified psychiatrist or physician before starting or adjusting any psychiatric medication.

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