Dudex 30 mg

DUDEX contains Dexlansoprazole, a proton pump inhibitor (PPI) that reduces the production of stomach acid. It works by blocking the gastric proton pump (H⁺/K⁺-ATPase) in the stomach lining, which provides long-lasting relief from acid-related conditions. In Pakistan, DUDEX is often used in the management of gastroesophageal reflux disease (GERD) and related digestive problems.

Primary Uses

DUDEX is commonly prescribed for:

• Heartburn and acid reflux (GERD)

• Healing and maintenance of erosive esophagitis

• Long-term management of acid-related conditions

• Relief of reflux symptoms such as difficulty swallowing and chest discomfort

• Supporting mucosal healing in the stomach and esophagus

Side Effects

Possible side effects may include:

• Headache

• Nausea or diarrhea

• Abdominal pain

• Fatigue or dizziness

• Skin rash

Rare but serious effects:

• Low magnesium levels

• Increased risk of bone fractures with long-term use

• Severe allergic reaction or liver function changes

Precautions & Warnings

• Avoid use if allergic to Dexlansoprazole or other PPIs.

• Use with caution in patients with liver disease, osteoporosis, or low magnesium levels.

• Not suitable for patients taking rilpivirine (an HIV medication).

• Long-term use may mask symptoms of more serious stomach problems, such as gastric cancer.

• Elderly patients may be more prone to side effects and require monitoring.

Contraindications

• Severe liver impairment

• Known hypersensitivity to PPIs

• Use with rilpivirine-containing medicines

Drug & Food Interactions

• May reduce absorption of medicines requiring stomach acid (e.g., ketoconazole, iron supplements).

• May interact with warfarin, phenytoin, methotrexate, diazepam (dose monitoring required).

• Avoid grapefruit juice, as it may interfere with metabolism.

• High-fat meals may delay absorption.

• Excessive alcohol, caffeine, and spicy foods may reduce effectiveness or worsen symptoms.

Storage & Handling

• Store at room temperature (below 30°C), in original packaging.

• Protect from sunlight, heat, and moisture.

• Keep out of reach of children.

• Dispose of expired or unused capsules responsibly.

FAQs

Q: What is DUDEX used for?
A: It is used to treat acid reflux, heartburn, GERD, and to promote healing of erosive esophagitis.

Q: Can I take it with food?
A: It is best taken before a meal, usually in the morning.

Q: Does DUDEX have long-term side effects?
A: Prolonged use may increase the risk of low magnesium, bone fractures, or vitamin B12 deficiency.

Q: Can I open the capsule?
A: If swallowing is difficult, the capsule can be opened and sprinkled on soft food, but it should not be crushed or chewed.

Doctor’s Review
Dr. Sana Ahmed, MBBS, FCPS – Gastroenterology

“DUDEX (Dexlansoprazole) is a proton pump inhibitor designed to provide 24-hour acid suppression, making it effective for managing persistent acid reflux and erosive esophagitis. By reducing stomach acid, it helps control recurrent heartburn and supports better sleep quality in patients with reflux-related symptoms. It is generally well tolerated, though long-term use requires caution due to potential risks such as low magnesium levels or bone-related changes. Regular monitoring and follow-up are recommended when therapy is extended.”

Disclaimer
This information is provided for educational and product awareness purposes only. It is not a medical prescription. Always consult a qualified physician or gastroenterologist before starting or adjusting any medication.