Itopride Hydrochloride is a gastrointestinal motility medicine used to relieve nausea, vomiting, bloating, and indigestion. It works by enhancing stomach and intestinal movement, helping food pass more quickly through the digestive system. This reduces reflux episodes and relieves discomfort caused by delayed gastric emptying.
Primary Uses
Itopride is commonly prescribed for:
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Functional dyspepsia (indigestion and bloating)
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Acid reflux and heartburn
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Nausea and vomiting
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Postoperative digestive discomfort
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Support in gastroparesis (delayed stomach emptying)
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Irritable bowel syndrome (IBS) with motility issues
Side Effects
Possible side effects include:
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Headache
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Dizziness or drowsiness
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Nausea or constipation
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Dry mouth
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Loss of appetite
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Fatigue
Rare but serious:
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Allergic reactions (rash, swelling)
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Changes in blood counts (very uncommon)
Precautions & Warnings
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Use with caution in elderly patients.
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Not recommended during pregnancy or breastfeeding without medical advice.
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Avoid in patients with intestinal obstruction or severe motility disorders.
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Should not be used in Parkinson’s disease without specialist supervision.
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May cause drowsiness; avoid driving until effects are known.
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Limit alcohol intake as it may worsen side effects.
Contraindications
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Allergy to Itopride or its components
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Children and adolescents under 18 years
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Severe kidney impairment or patients on dialysis
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History of severe stomach or intestinal obstruction
Drug Interactions
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Anticholinergic medicines – may reduce effectiveness
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CNS depressants (e.g., sedatives, alcohol) – may increase drowsiness
Food Interactions
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Can be taken with or without food
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Food may improve absorption in some patients
Dosage Guidance
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Usual adult dose: 50mg, three times daily (before meals)
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Dose may vary based on condition and doctor’s advice
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Do not exceed prescribed quantity
Missed dose: Take as soon as remembered, unless close to next dose. Do not double dose.
Overdose: May cause dizziness, low blood pressure, or fainting — requires urgent medical care.
Storage & Disposal
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Store at room temperature (15–25°C), away from heat and sunlight
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Keep in original packaging to protect from moisture
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Dispose of expired tablets safely; keep out of reach of children
Doctor’s Review
Dr. Farhan Siddiqui, MBBS, FCPS – Gastroenterology
I prescribe Itopride for patients struggling with indigestion, bloating, and delayed stomach emptying. It improves gastric motility and provides relief from nausea and reflux symptoms. In my practice, most patients tolerate it well, with only mild side effects like headache or dizziness. I avoid it in patients with Parkinson’s disease or those already on multiple central nervous system drugs. When used correctly, Itopride is a dependable option for functional digestive disorders.
Disclaimer
This information is provided for educational and product awareness purposes only. It is not a medical prescription. Always consult a qualified physician before starting or adjusting any gastrointestinal medication.
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