Endol

Endol 650mg Tablet is an analgesic and antipyretic medicine containing Paracetamol (Acetaminophen) as its active ingredient. It is widely used for the relief of fever, headache, toothache, menstrual pain, muscle aches, joint pain, and post-surgical discomfort. Paracetamol works by blocking the release of certain natural chemicals (prostaglandins) in the brain that cause pain and fever. It is generally well tolerated and considered safe when taken at the recommended dose. Endol 650mg is also the preferred pain and fever reliever during pregnancy and breastfeeding under medical guidance.

Ingredients

• Paracetamol (Acetaminophen) 650mg.

Drug Class

• Analgesic / Antipyretic

Dosage Form

• Tablet

Uses

Endol 650mg Tablet is indicated for:

• Reducing fever (pyrexia).

• Relieving headaches and migraines.

• Toothache and dental pain.

• Menstrual cramps (dysmenorrhea).

• Muscle and joint pain.

• Cold and flu-related pain.

• Post-surgical or injury-related mild to moderate pain.

Dosage

• Adults: 500–650mg every 4–6 hours as needed. Maximum daily dose: 4000mg.

• Children (as per doctor’s advice): Dose based on age and body weight.

• Always follow the dosage prescribed by your doctor.

In Case of Overdose

Overdose can cause serious liver damage. Symptoms may include nausea, vomiting, sweating, stomach pain, and yellowing of eyes or skin. Seek immediate medical attention.

Missed Dose

If you miss a dose, take it when you remember. If it’s almost time for the next scheduled dose, skip the missed one. Do not double the dose.

How To Use

• Swallow the tablet whole with a glass of water.

• Maintain at least a 4–6 hour gap between doses.

• Can be taken with or without food.

When Not to Use

Avoid Endol 650mg Tablet if:

• You are allergic to Paracetamol or Acetaminophen.

• You have severe liver disease or active liver failure.

• You suffer from severe kidney impairment.

• You are already taking another medicine containing Paracetamol.

Side Effects

Paracetamol is generally safe, but rare side effects may include:

• Skin rash or itching.

• Allergic reactions (swelling of face/lips, difficulty breathing).

• Blisters or peeling skin (very rare).

• Blood-related problems (low blood counts, rare).

• Liver injury in case of overdose.

Precautions & Warnings

• Do not exceed the recommended daily dose.

• Use cautiously in patients with liver or kidney problems.

• Safe for use in pregnancy and breastfeeding when prescribed.

• Avoid alcohol while taking this medicine.

• Always check labels to avoid taking multiple paracetamol products together.

Drug Interactions

Endol 650mg may interact with:

• Warfarin and anticoagulants: Long-term use increases bleeding risk.

• Carbamazepine, Phenytoin, Rifampicin: Increases liver toxicity risk.

• Metoclopramide/Domperidone: May speed up absorption of paracetamol.

• Cholestyramine: Reduces absorption of paracetamol.

Storage & Disposal

• Store in a cool, dry place at room temperature.

• Protect from moisture, heat, and sunlight.

• Keep out of reach of children and pets.

• Dispose of expired or unused tablets safely; do not flush into drains.

Quick Tips

• Use the lowest effective dose for the shortest duration.

• Do not combine with other painkillers containing Paracetamol.

• If fever persists for >3 days or pain >5 days, consult your doctor.

• Stay hydrated while on medication.

Doctor’s Review
Dr. Hammad Ali, MBBS, FCPS

“Endol 650mg (Paracetamol) is widely used for relief from fever and mild to moderate pain. It is generally well tolerated and is considered safe for use during pregnancy and breastfeeding when taken as directed. The key precaution is to avoid exceeding the recommended dosage, as overdose can result in serious liver damage. Maintaining proper intervals between doses and seeking medical advice if symptoms persist are important for safe use. Overall, Endol remains a trusted and dependable option for managing common pain and fever.”

Disclaimer
This information is provided for educational and product reference purposes only. It is not a substitute for medical advice, diagnosis, or treatment. Always consult a qualified doctor or pharmacist before starting, changing, or stopping any medication.