Epicar

Description

Carbamazepine is an anticonvulsant medicine that helps stabilize overactive nerve signals in the brain. It works by blocking voltage-gated sodium channels, which prevents abnormal electrical discharges and reduces the frequency and intensity of seizures. Beyond epilepsy, it is also used to manage mood disorders such as bipolar depression when other treatments like lithium are ineffective.

Composition / Active Ingredient

Carbamazepine

Drug Class

Anticonvulsant

Dosage Form

Tablet

Uses

• Epilepsy (Seizure control)

• Bipolar disorder or manic depressive episodes (especially when lithium is not effective)

Doctor Insight

Carbamazepine is often preferred when both seizure control and mood stabilization are needed, but it requires careful monitoring. Response and tolerance vary widely among patients, and liver function or blood levels are usually assessed periodically to ensure safe use.

Dosage

• Adults: 200–400 mg twice daily (maximum 1600 mg/day)

• Children 6–12 yrs: 100–200 mg twice daily

• Children below 6 yrs: 10–20 mg/kg/day divided in doses

How to Take

Take orally with food to reduce stomach discomfort. Use at consistent intervals and do not stop suddenly unless advised by a doctor.

Missed Dose

Take when remembered unless close to the next scheduled dose. Do not double dose.

Overdose

May cause severe neurological or gastrointestinal symptoms. Seek emergency medical help immediately.

Side Effects

Possible effects include headache, dizziness, drowsiness, stomach upset, blurred vision, dry mouth, swelling, or fatigue. Rare but serious reactions include skin rashes, liver changes, blood disorders, or kidney issues.

Precautions

Use carefully in patients with heart disease, liver/kidney impairment, glaucoma, or history of severe allergic reactions. Regular lab monitoring is usually recommended.

Drug Interactions

• CYP3A4 inducers (e.g., rifampin): May reduce Carbamazepine levels

• CYP3A4 inhibitors (e.g., ketoconazole): May increase its levels

• Other anticonvulsants (e.g., phenytoin): May affect dosage stability

Food Interactions

Take with food if stomach irritation occurs. Avoid grapefruit juice as it may increase blood levels of the drug.

Storage

Store at room temperature away from light and moisture. Keep in original pack and out of children’s reach.

Disclaimer

This information is for educational and reference purposes only and not medical advice. Always consult a licensed healthcare professional before starting or adjusting Carbamazepine.