Genticyn Topical Discontinue

Topical gentamicin shows up in Pakistani clinics and pharmacies, from skin OPDs at Jinnah Hospital in Karachi to dermatology setups in Lahore, where docs use it for bacterial skin infections when cultures point to sensitive bugs. PMDC standards note its role in local infections, but resistance is a growing issue in areas with heavy antibiotic use. This lays out uses, application, side effects—pulled from practices here, not a call to apply it solo.

Basic Product Details

• Form and Strength: 0.1% or 0.3% cream or ointment tubes.
• Packaging: Tubes of 15g or 30g; generics in single packs or boxes.
• Pricing: PKR 50-150 per tube, depending on brand—stock at Dawaai.pk, Servaid, or local chemists.
• Brands in Pakistan: Genticyn, Gentamed, or PMDC-approved generics from Hudson or Sami Pharma.

Ingredients

• Active Ingredient: Gentamicin sulfate (equivalent to 1 mg/g or similar).
• Excipients: Petrolatum base for ointments, or cream bases with preservatives—check tube label.

Drug Class

Topical Aminoglycoside Antibiotic.

How It Functions

Gentamicin stops bacterial protein synthesis by binding to their ribosomes, killing off Gram-positive and some Gram-negative skin bugs. In Pakistan’s humid climate, where folliculitis or impetigo spreads fast, it’s targeted for confirmed sensitive strains, but docs swab first due to resistance patterns.

Common Applications

Per local derm guidelines:

• Bacterial skin infections like impetigo, folliculitis, or infected wounds.
• Secondary infections in eczema, psoriasis flares, or burns.
• Sores or ulcers from diabetes—common in Pakistani patients.

Only for lab-confirmed sensitive bacteria; resistance limits broader use.

Dosage Form

Cream or ointment applied thinly to affected skin 2-4 times daily, as prescribed.

Potential Side Effects

Common local reactions:

• Redness or itching at site.
• Mild irritation or dryness.

Serious from hospital reports: Severe allergy (rash, swelling, breathing issues), or new fungal overgrowth if bacteria clear but yeast takes hold. Stop use and see doc if infection worsens or no improvement in 3-5 days.

Key Warnings and Precautions

PMDC notes:

• Eyes/Nose/Mouth: Avoid—only intact skin.
• Resistance: Not for viral/fungal issues; culture if possible.
• Pregnancy/Breastfeeding: Limited data—discuss risks; minimal absorption but caution.
• Large Areas: Limit to small zones to cut systemic risks.
• Kids/Elderly: Standard, but monitor for irritation.

Clean area first, remove crusts for impetigo. Wash hands after.

When It’s Not Suitable (Contraindications)

Skip if:

• Allergy to gentamicin or aminoglycosides.
• Viral, fungal, or resistant bacterial infections.

Drug Interactions

Minimal systemic, but flag:

• Other topicals—avoid mixing without doc okay.
• No major oral food/alcohol ties.

In Case of Overdose

Rare with topical, but excessive use might cause irritation—rinse off, seek care if systemic symptoms.

Missed Dose

Apply when remembered; don’t double up.

Storage and Disposal

Room temp (15-30°C), tight cap, away from heat/kids. Dispose unused via pharmacy, not drain.

Quick Tips

• Prescription only—doc confirms bug sensitivity.
• Thin layer, cover if needed.
• Finish course to prevent resistance.

Doctor Review

Derm specialists at PIMS Islamabad or Liaquat National in Karachi pick topical gentamicin for localized infections where oral antibiotics aren’t needed, but they stress sensitivity testing amid rising resistance—often pair with hygiene advice for boils or infected scratches common in dusty areas.

Laboratory Screening

If persistent:

• Skin swab cultures for resistance.
• Allergy patch if reaction suspected.

This maps topical gentamicin’s use in Pakistan’s skin care—facts for context, not home treatment.

Disclaimer: This is product information only, not a prescription or diagnosis. Consult a qualified Pakistani doctor before using topical gentamicin to ensure it’s safe. Seek immediate care for severe symptoms like swelling, breathing issues, or worsening infection.