Glifen contains glibenclamide, a sulfonylurea medicine used to manage type 2 diabetes. It helps lower blood sugar by stimulating the pancreas to release more insulin. This improves glucose control when diet, exercise, and lifestyle measures alone are not enough. Glifen is not recommended for type 1 diabetes or diabetic ketoacidosis.
Primary Uses
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Type 2 diabetes mellitus.
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Blood sugar management in adults when lifestyle control alone is insufficient.
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Can be used in combination with other oral antidiabetic medicines if required.
How to Use
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Take orally with water, preferably with meals.
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Swallow whole; do not chew or crush.
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Take at the same time daily to maintain blood sugar stability.
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Always follow the dose prescribed by your doctor.
Side Effects
Some patients may experience:
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Low blood sugar (dizziness, sweating, palpitations, blurred vision).
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Stomach upset or nausea.
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Skin rash or itching (rare).
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Abnormal liver or kidney function (rare, with prolonged use).
Warnings and Precautions
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Not recommended in pregnancy; if absolutely required, discontinue at least 2 weeks before delivery.
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Avoid during breastfeeding unless advised by a doctor.
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May cause dizziness; avoid driving or operating machinery if affected.
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Patients with liver or kidney disease may need dose adjustments.
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Avoid alcohol as it can worsen side effects and cause hypoglycemia.
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Monitor blood glucose regularly and maintain consistent meal timings.
Contraindications
Do not use Glifen if you have:
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Allergy to glibenclamide or related medicines.
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Severe kidney or liver impairment.
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Diabetic ketoacidosis or pre-coma state.
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Type 1 diabetes.
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Heart or severe breathing disorders.
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History of heavy alcohol intake.
FAQS
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Which class of medicine is Glifen?
It belongs to sulfonylureas, a group of oral antidiabetics. -
Does it cause low blood sugar?
Yes, especially if meals are skipped. Always take it with food. -
What if I miss a dose?
Take it with your next meal if not too late. If it’s almost time for the next dose, skip the missed one. Do not double dose. -
Is it safe for elderly patients?
Yes, but requires careful dose monitoring as older adults are more sensitive to low sugar. -
Can it be used with insulin?
Only if prescribed by your doctor. Combining with insulin increases the risk of hypoglycemia.
Storage
Store at room temperature (18–25°C), away from moisture, light, and heat. Keep out of children’s reach.
Doctor’s Review
Dr. Ayesha Malik – Consultant Endocrinologist
“Glifen is an oral medicine for type 2 diabetes that helps lower blood sugar effectively. Patients must be aware of the risk of hypoglycemia and avoid skipping meals. Elderly patients require closer monitoring, as they are more prone to low blood sugar episodes.”
Disclaimer
This information is for product knowledge only and does not replace medical advice. It is not a prescription. Always consult your doctor before starting or stopping any medicine.

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