Gonal F

Gonal-F contains follitropin alfa, a laboratory-made version of follicle-stimulating hormone (FSH). It is widely used in fertility treatment for women and men. In women, it helps the ovaries develop eggs, either to trigger ovulation or to prepare for assisted reproduction such as IVF. In men, it helps stimulate sperm production when natural FSH levels are low.

Primary Uses

• Fertility treatment in women undergoing assisted reproduction (IVF, ICSI).

• Inducing ovulation in women with ovulation problems.

• Treating male infertility linked with low FSH levels.

How to Use

• Injected under the skin (subcutaneous injection), usually in the thigh or abdomen.

• Doses are individualized and adjusted after blood tests and ultrasounds.

• Should only be used under supervision of a fertility specialist.

• Do not change the dose or stop treatment without your doctor’s advice.

Side Effects

Common side effects may include:

• Headache.

• Stomach pain or bloating.

• Nausea, vomiting, or diarrhea.

• Ovarian cysts in women.

• Breast tenderness.

• Redness, swelling, or itching at injection site.

• Fatigue.

Serious but less common side effects include:

• Ovarian hyperstimulation syndrome (OHSS) – abdominal swelling, sudden weight gain, breathing difficulty.

• Blood clots (rare) – chest pain, severe headache, weakness, or vision problems.

• Severe allergic reactions – swelling of face or throat, rash, difficulty breathing.

Seek medical attention if severe symptoms occur.

Warnings & Precautions

• Not to be used if you are pregnant or breastfeeding.

• Not recommended for women with ovarian failure, uncontrolled thyroid or adrenal disorders, or hormone-related cancers.

• Can increase the chance of multiple pregnancy (twins/triplets).

• Requires strict monitoring with blood tests and ultrasounds.

• People with blood clotting disorders or a family history of clots should inform their doctor.

Contraindications

Do not use Gonal-F if you have:

• Allergy to follitropin alfa or any FSH product.

• Unexplained vaginal bleeding.

• Ovarian cysts not caused by PCOS.

• Tumors of the ovaries, uterus, pituitary, or hypothalamus.

• Primary ovarian or testicular failure.

FAQs

Can Gonal-F be used at home?
Yes, but only after your doctor or nurse shows you how to inject safely.

Does it guarantee pregnancy?
No, but it improves the chances when used as part of a fertility treatment plan.

How should it be stored?

• Vials: Store in the refrigerator or at room temperature (2–25°C), protected from light.

• Pens: Store in refrigerator (2–8°C). After opening, pens may be kept at room temperature (20–25°C) for up to 3 months. Do not freeze.

Can men use Gonal-F?
Yes, it is sometimes prescribed for men with infertility due to low FSH levels.

What if I miss a dose?
Do not double up. Call your doctor immediately for guidance.

Storage

• Keep refrigerated (2–8°C).

• Do not freeze.

• Protect from light.

• Keep away from children.

Doctor’s Review – Dr. Sara Khan, Consultant Gynecologist & Fertility Specialist:
“Gonal-F supports ovulation and assisted reproduction but requires close monitoring to avoid OHSS, with dosage strictly following the fertility plan.”

Disclaimer

This is product information only, not a prescription. Gonal-F should only be used under the guidance of a qualified fertility specialist. Always consult your doctor before starting or stopping this medicine.