Ivagen 5mg Tablets (28’s Pack)

Brand: Genix Pharma (Pvt.) Ltd.
Generic Name: Ivabradine 5mg
Ivagen (Ivabradine) works by selectively inhibiting the “funny” current (If current) in the sinoatrial (SA) node, which controls the heart’s pacemaker activity. By slowing the heart rate without reducing heart muscle contractility, Ivabradine helps relieve chest pain, improves exercise capacity, and reduces hospitalizations in patients with chronic heart failure and stable angina.

Primary Uses

Ivabradine is prescribed for:

• Stable angina (to reduce frequency of chest pain).

• Chronic heart failure (to lower hospitalization risk).

• Controlling heart rate in patients intolerant to beta-blockers.

• Improving exercise capacity and quality of life in selected cardiac patients.

How to Use

• Take as prescribed, usually one tablet twice daily.

• Swallow whole with a glass of water.

• Maintain a consistent routine (same time each day).

• Do not crush, chew, or break the tablet.

Missed Dose / Overdose

• Missed Dose: Take as soon as you remember unless it’s almost time for the next dose. Do not double dose.

• Overdose: May cause severe bradycardia (slow heart rate) or low blood pressure. Seek emergency care immediately.

When Not to Use

Do not use Ivabradine if you have:

• Allergy to Ivabradine or its components.

• Resting heart rate < 60 bpm.

• Severe hypotension or cardiogenic shock.

• Sick sinus syndrome or severe heart block (without pacemaker).

• Severe liver disease.

• Unstable angina or recent decompensated heart failure.

• Severe aortic stenosis.

Side Effects

Common side effects may include:

• Slow heart rate (bradycardia).

• Headache, dizziness, fatigue.

• Visual disturbances (blurred vision, flashes of light/phosphenes).

• Nausea or stomach upset.

• High blood pressure during exercise.

• Skin rash (rare).

Precautions & Warnings

• Not recommended for patients below 18 years.

• Use cautiously in elderly patients; monitoring is advised.

• May cause temporary visual disturbances; avoid driving until effects are known.

• Inform your doctor if you have arrhythmias, liver issues, or other heart conditions.

• Pregnant and lactating women should consult their doctor before use.

Drug & Food Interactions

• Avoid with verapamil, diltiazem, and strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin).

• May interact with beta-blockers, digoxin, and anti-arrhythmic drugs.

• Avoid grapefruit, Seville oranges, pomelos (increase Ivabradine levels).

• Limit alcohol and caffeine (may alter heart effects).

• Herbal products like St. John’s Wort may reduce effectiveness.

Storage & Disposal

• Store at room temperature in a dry place, away from sunlight and moisture.

• Keep out of reach of children and pets.

• Do not flush unused tablets; follow safe disposal guidelines or ask a pharmacist.

Quick Tips

• Take at the same time every day for best results.

• Continue even if you feel well; do not stop abruptly.

• Avoid driving at night if you experience visual light flashes.

• Inform your doctor about all medicines and supplements you are using.

Doctor’s Review

Dr. Sara Hussain, Consultant Cardiologist
“Ivabradine is an excellent option for patients with chronic stable angina or heart failure who cannot tolerate beta-blockers. It lowers heart rate without affecting blood pressure or cardiac contractility. However, it must be prescribed carefully, with regular monitoring of heart rate and visual side effects.”

Disclaimer

This information is provided for educational purposes only. It does not replace medical advice. Always consult your physician before starting, adjusting, or stopping this medication.