Mediphrine

Mediphrine 10% Drops contain Phenylephrine, a fast-acting decongestant used to relieve nasal and sinus congestion caused by the common cold, flu, hay fever, or allergies. In ophthalmology, it is also used as a mydriatic and cycloplegic agent to dilate the pupil for eye examinations.

Primary Uses

• Relief of nasal and sinus congestion

• Supportive treatment for allergic rhinitis and hay fever

• Ophthalmic use as a pupil dilator during diagnostic eye procedures

• Sometimes prescribed for hemorrhoids (local application)

Indications

Mediphrine may be prescribed for:

• Blocked or stuffy nose caused by cold, flu, or allergies

• Sinus congestion and related discomfort

• As an eye drop for pupil dilation before examination or minor procedures

How It Works

Phenylephrine works by narrowing blood vessels in the nose, sinuses, and eyes. This reduces swelling, congestion, and pressure. In the eye, it relaxes muscles to dilate the pupil, allowing better visibility during eye exams.

Side Effects

Most patients tolerate Mediphrine well, but some side effects may occur:

• Mild stomach upset or nausea

• Trouble sleeping, restlessness, or nervousness

• Headache or dizziness

• Rare allergic reactions (itching, swelling, difficulty breathing)

• Temporary eye irritation when used as drops

Precautions & Warnings

• Avoid if allergic to Phenylephrine or any of its components

• Use with caution in patients with liver, kidney, heart disease, or high blood pressure

• Pregnant and breastfeeding women should use only on doctor’s advice

• May cause drowsiness — avoid driving or operating machinery after use

• Alcohol can increase side effects and should be avoided

Contraindications

• Known allergy to Phenylephrine

• Patients with severe hypertension, glaucoma, or certain eye conditions should not use without specialist advice

Storage

Keep at room temperature (18–25°C), away from direct light and moisture. Keep out of reach of children.

Doctor’s Overview

Dr. Imran Siddiqui – Consultant ENT Specialist, MBBS, FCPS

Mediphrine is used for quick relief of nasal congestion from colds or allergies and is also applied for pupil dilation in eye exams. It works fast but should not be overused, as excessive use may worsen symptoms or cause irritation.

Disclaimer

This overview is for educational purposes only. Mediphrine is a prescription medicine and should be used only under the supervision of a qualified healthcare professional.