Description
This medicine combines three active ingredients: Paracetamol, which reduces pain and fever; Aspirin, which works as a pain reliever and anti-inflammatory agent; and Caffeine, which boosts the pain-relieving effect of the other two medicines. Together, they help provide effective relief from pain, fever, and inflammation.
Drug Class
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Analgesic, Antipyretic, Anti-inflammatory.
Uses
Doctors prescribe this medicine for:
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Headache and migraine.
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Toothache and menstrual pain.
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Muscle aches, sprains, and back pain.
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Pain and fever in colds or flu.
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Joint pain and arthritis-related discomfort.
How to Use
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Swallow the tablet whole with water.
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Take after meals to reduce stomach irritation.
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Use only in the dose and duration advised by your doctor.
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Do not exceed the recommended dose.
When Not to Use
Avoid this medicine if you have:
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Allergy to paracetamol, aspirin, or caffeine.
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Stomach ulcers or bleeding disorders.
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Severe liver or kidney disease.
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Asthma triggered by aspirin.
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Severe heart disease or uncontrolled blood pressure.
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Pregnancy (especially last trimester) or breastfeeding.
Precautions
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Do not combine with alcohol. (risk of liver damage and stomach bleeding)
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Use with caution if you have a history of stomach or liver problems.
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Not recommended for children under 16 years unless prescribed.
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May cause drowsiness or restlessness — avoid driving if affected.
Possible Side Effects
Some people may experience:
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Nausea, vomiting, or stomach upset.
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Dizziness or headache.
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Skin rash or itching.
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Increased heartbeat or restlessness.
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Trouble sleeping. (insomnia)
Seek medical help if any severe reaction occurs.
Drug Interactions
Avoid combining with:
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Blood thinners (e.g., warfarin)
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Other NSAIDs or painkillers
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Alcohol or sedatives
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Some antidepressants (SSRIs)
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Certain anti-seizure and antifungal medicines
Food Interactions
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Avoid excess caffeine. (coffee, tea, energy drinks)
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Avoid alcohol.(increases risk of liver damage and stomach bleeding)
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Take after a light meal to reduce stomach irritation.
Storage
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Store at room temperature, away from heat and moisture.
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Keep in original packaging.
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Keep out of reach of children.
Doctor’s Overview — Dr. Imran Saleem, MBBS, FCPS
This combination medicine is used for short-term pain relief in conditions like headache and migraine. Caffeine enhances the pain-relieving effect, but patients must avoid overuse, as the risk of side effects and overdose is higher due to multiple active ingredients.
Disclaimer
This overview is for educational purposes only. This medicine is prescription-only and should be used only under the supervision of a qualified healthcare professional.

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