Description
Orlistat helps in weight management by blocking some of the fat you eat from being absorbed in the intestine. This reduces calorie intake and supports weight loss when combined with a balanced diet and regular physical activity.
Uses
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Weight loss in overweight and obese patients
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Helps prevent weight regain after weight loss
Dosage
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One capsule three times daily with a meal that contains fat
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Take during the meal or within 1 hour after eating
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Do not take on an empty stomach
Overdose
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May cause severe stomach upset, oily stools, or bloody stools
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Can be serious or life-threatening in rare cases
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Seek medical help immediately if overdose is suspected
Missed Dose
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Take as soon as you remember, within 1 hour of eating a meal
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If more than 1 hour has passed, skip it and continue with the next scheduled dose
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Do not double the dose
How to Use
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Swallow with a full glass of water
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Take only with meals that contain fat
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Use along with a reduced-calorie, low-fat diet for best results
When Not to Use
Do not use if you are:
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Pregnant or breastfeeding
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Allergic to Orlistat
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Having chronic malabsorption or gallbladder problems
Side Effects
Common:
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Oily or fatty stools
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Gas with discharge
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Loose stools
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Abdominal or rectal pain
Rare but serious:
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Blood in urine
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Severe stomach or back pain
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Signs of liver problems (yellow skin or eyes, dark urine)
Precautions
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Tell your doctor if you have liver, kidney, thyroid, or gallbladder disease
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Do not take with very high-fat meals (increases risk of side effects)
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Long-term use may lower levels of some vitamins; your doctor may suggest a multivitamin supplement
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Avoid alcohol if it worsens side effects
Drug Interactions
Inform your doctor if you are taking:
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Anti-diabetic medicines
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Cyclosporine
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Amiodarone
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Anti-seizure medicines
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HIV medicines
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Vitamin supplements (take at least 2 hours before or after Orlistat)
Storage & Disposal
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Store at room temperature (below 25°C)
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Keep away from heat, moisture, and direct sunlight
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Keep out of reach of children
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Do not use after expiry
Quick Tips
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Follow a low-fat diet to reduce side effects
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Exercise regularly for better weight loss results
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Take a multivitamin at bedtime if advised by your doctor
Dr. Hira Qayyum, Endocrinologist
MBBS, FCPS (Medicine), Diabetes & Obesity Specialist – Islamabad
Dr. Hira Qayyum often recommends Orlistat for patients struggling with obesity, particularly when diet and exercise alone are not enough. It is effective for those committed to a low-fat, calorie-controlled diet. The most common side effect is oily stools, which typically improves with a reduction in fatty foods. For long-term use, a multivitamin is advised, as Orlistat can reduce the absorption of some vitamins. It is not suitable for pregnant women or individuals with certain digestive issues. When used alongside proper lifestyle changes, Orlistat is a safe and effective weight loss option.
Medical Disclaimer: This product information, including the doctor’s review, is for educational purposes only. It is not a prescription. For dosage, safety, and suitability, always consult a qualified healthcare professional.

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