Penorit

Description

Penorit Tablets are a combined oral contraceptive containing Ethinyloestradiol (synthetic estrogen) and Norethisterone (progestin). Together, they prevent ovulation, thicken cervical mucus to block sperm entry, and make the uterine lining less receptive to implantation. Apart from contraceptive use, they are also prescribed for certain menstrual and hormonal conditions.

Ingredients

• Ethinyloestradiol

• Norethisterone

Drug Class

Oral contraceptive

Uses

This medicine is used for:

• Preventing pregnancy

• Managing endometriosis

• Regulating irregular or heavy menstrual bleeding

• Relieving menopausal symptoms (e.g., hot flashes, dryness)

• Reducing risk of ovarian and endometrial cancers (in long-term use)

• Improving hormonal balance and menstrual cycle regularity

• Treating acne linked to hormonal imbalance

How to Use

• Swallow one tablet daily at the same time each day with water.

• Usually taken for 21 days, followed by a 7-day gap (or as prescribed).

• Can be started on the first day of the menstrual cycle or as directed by the doctor.

• Do not double the dose if a tablet is missed; follow the doctor’s instructions.

Missed Dose

• If less than 12 hours late, take the missed dose immediately.

• If more than 12 hours late, skip the missed dose and continue the next one at the scheduled time.

• For multiple missed doses, consult your doctor.

Overdose

Symptoms may include nausea, vomiting, breast tenderness, dizziness, or abdominal pain. Seek medical advice promptly if overdose is suspected.

Side Effects

Common side effects:

• Nausea and vomiting

• Headaches or migraines

• Breast tenderness

• Mood changes

• Skin changes (acne, pigmentation)

• Weight fluctuations

Serious (rare) side effects:

• Blood clots

• Stroke or heart attack (especially in smokers or high-risk patients)

• Increased blood pressure

Warnings & Precautions

• Pregnancy: Contraindicated; not to be used if pregnant.

• Breastfeeding: Consult a doctor before use.

• Medical history: Inform your doctor if you have blood clotting disorders, stroke, heart disease, liver disease, migraines, or unexplained vaginal bleeding.

• Smoking increases risk of serious side effects.

• Regular check-ups are advised to monitor blood pressure and overall health.

When Not to Use

Do not use this medicine if you have:

• History of blood clots, stroke, or heart attack

• Estrogen-dependent cancers (e.g., breast, uterine)

• Severe liver disease

• Uncontrolled high blood pressure

• Pregnancy

• Severe migraines or blood disorders

Drug Interactions

This medicine may interact with:

• Certain antibiotics and antifungal medicines

• Antiepileptic drugs (e.g., phenytoin, carbamazepine)

• Rifampicin and griseofulvin

• HIV medicines

• Herbal remedies like St. John’s Wort

• Blood sugar–lowering drugs (may need dose adjustment)

Food Interactions

• Avoid grapefruit juice, which may affect hormone metabolism.

• Limit alcohol, as it may interfere with liver metabolism of hormones.

• Maintain a consistent diet for stable absorption.

Storage & Disposal

• Store at room temperature (around 25°C).

• Keep in original packaging, away from light, heat, and moisture.

• Do not dispose of in household waste; follow local disposal guidelines.

• Keep out of children’s reach.

Quick Tips

• Take at the same time daily for best results.

• Do not smoke while using this medicine.

• Report unusual symptoms like severe headaches, chest pain, or vision changes immediately.

• This medicine does not protect against sexually transmitted infections (STIs).

Doctor’s Review

Dr. Nadia Hussain, Gynecologist
MBBS, FCPS (Gynecology & Obstetrics), Karachi

“Ethinyloestradiol and Norethisterone is a reliable oral contraceptive that also benefits patients with irregular periods, endometriosis, and hormonal acne. It works effectively when taken regularly. However, it carries risks of blood clots and should be avoided in smokers, women with heart disease, or those with a history of stroke. With proper medical guidance, it is safe and effective for most women.”

Medical Disclaimer

This product information, including the doctor’s review, is for educational purposes only. It is not a prescription. Always consult a qualified healthcare professional before starting or changing any medicine.