Introduction
Provin 500mg Tablet contains Naproxen (500mg) as its active ingredient, a powerful NSAID (Non-Steroidal Anti-Inflammatory Drug). It is primarily used for pain relief and to reduce inflammation. This medication is effective in treating various conditions like rheumatoid arthritis, osteoarthritis, gout, menstrual pain, migraine, and musculoskeletal pain.
It works by inhibiting enzymes that cause inflammation, pain, and fever, providing relief for individuals suffering from these conditions.
Primary Uses
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Pain Relief: Reduces pain in conditions such as arthritis, muscle pain, and more.
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Inflammation Reduction: Decreases inflammation in conditions like rheumatoid arthritis, osteoarthritis, and gout.
Indications
Provin 500mg Tablet is used for:
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Rheumatoid Arthritis
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Osteoarthritis
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Ankylosing Spondylitis
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Musculoskeletal Disorders
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Acute Gout
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Dysmenorrhea (Painful Menstrual Cramps)
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Migraine
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Post-operative Pain
Side Effects
Possible side effects may include:
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Gastrointestinal upset (e.g., nausea, abdominal pain, bleeding, ulceration)
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Headache, dizziness
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Tinnitus (ringing in ears)
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Edema (fluid retention), hypertension (high blood pressure)
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Cardiac and respiratory issues (dyspnea, impaired hearing, visual disturbances)
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Skin reactions, allergic reactions (rash, itching)
If any side effects persist or worsen, consult your doctor.
Warnings
Pregnancy
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Not recommended during the last trimester of pregnancy.
Lactation
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Contraindicated for breastfeeding mothers.
Alcohol
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Avoid alcohol consumption while taking this medication.
Precautions
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Use cautiously in patients with renal (kidney) or hepatic (liver) impairment, asthma, hypertension, or elderly individuals.
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Long-term use should be monitored, with the lowest effective dose for short-term therapy.
Contraindications
Do not use in patients with:
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Aspirin or anti-inflammatory induced allergies
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Active gastric/duodenal ulcers
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Severe heart failure, hemorrhage, bleeding disorders
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Renal or hepatic impairment
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Creatinine clearance < 20ml/min
Dosage and Usage
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Take Immediately After Meals: To minimize gastrointestinal irritation.
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Do Not Crush or Chew: Swallow the tablet whole.
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Do Not Lie Down: Avoid lying down for at least 15-20 minutes after taking the medication.
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Maximum Duration: Do not use for more than 10 days without consulting a healthcare provider.
Doctor’s Review
Dr. Sana Malik, MD, Rheumatologist, Pakistan:
“Provin 500mg Tablet (Naproxen) is a well-established anti-inflammatory medication, effective for treating conditions such as rheumatoid arthritis, osteoarthritis, and musculoskeletal pain. It helps manage pain and inflammation, providing relief for patients suffering from these chronic conditions. However, as with all NSAIDs, it should be used at the lowest effective dose for the shortest duration necessary, and patients should monitor for any gastrointestinal or cardiovascular side effects.”
FAQ
Q1. What is naproxen used to treat?
Naproxen is used to reduce inflammation and pain in joints and muscles.
Q2. How to store this medicine?
Store at room temperature (18-25°C). Keep away from children, light, and moisture.
Q3. Does naproxen increase blood pressure?
It may cause a slight increase in blood pressure.
Q4. Is naproxen a muscle relaxant?
No, naproxen is an NSAID, not a muscle relaxant.
Q5. What are the precautions?
Patients with heart, kidney, liver issues, high blood pressure, asthma, or elderly individuals should use naproxen cautiously.
Q6. How to administer this medicine?
Take naproxen after meals. The dosage depends on the condition being treated, so always follow your doctor’s guidance.
Q7. Is it safe to take naproxen every day?
Long-term use is generally not recommended. Follow your doctor’s advice for duration.
Disclaimer
This information is for educational purposes only and is not a substitute for professional medical advice. Always consult your healthcare provider before starting or discontinuing any medication.

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