Risp

Description

Risp 1mg contains Risperidone, an atypical antipsychotic used in the management of schizophrenia and related psychotic symptoms. Its effect is believed to involve dopamine (D2) and serotonin (5HT2) receptor antagonism, helping stabilize mood, perception, and thought processes.

Uses

• Treatment of schizophrenia.

Dosage

Dose varies depending on individual medical assessment. Only to be used under medical supervision.

How It Works

Risperidone blocks dopamine and serotonin receptors, helping reduce hallucinations, delusions, and disorganized behavior. Its effect results from both Risperidone and its metabolite, 9-hydroxyrisperidone (Paliperidone).

Side Effects

May include:

• Increased mortality risk in elderly patients with dementia-related psychosis.

• Stroke or cerebrovascular events in dementia patients.

• Neuroleptic malignant syndrome (rare but serious).

• Tardive dyskinesia (involuntary movements).

• Metabolic changes (blood sugar, cholesterol, weight gain).

• Hormonal imbalance (hyperprolactinemia).

• Low blood pressure (orthostatic hypotension), dizziness and falls.

• White blood cell reduction (leukopenia, neutropenia).

• Sedation, motor impairment, or seizures.

• Difficulty swallowing.

• Prolonged erection (priapism).

• Temperature regulation disturbances.

When Not to Use

Avoid in:

• Known allergy to Risperidone or Paliperidone.

• Previous hypersensitivity reactions with similar drugs.

Precautions

• Higher mortality risk in elderly dementia-related psychosis.

• Monitor for cardiac, metabolic, and neurological changes.

Warnings

1. Neuroleptic Malignant Syndrome (NMS) — serious medical condition requiring immediate intervention.

2. Tardive Dyskinesia — involuntary, potentially irreversible movements.

3. Metabolic Risks — weight gain, blood sugar increase, dyslipidemia.

Drug Interactions

May interact with:

• Fluoxetine, Paroxetine (SSRIs).

• Carbamazepine (enzyme inducer).

• Cimetidine, Ranitidine.

• Erythromycin, Ketoconazole, Verapamil.

• Levodopa, Dopamine agonists.

• Furosemide, Rifampicin, Anticholinergics.

Storage

Store at room temperature, away from heat and light.

Disclaimer

This product profile is for information only and not a treatment recommendation. Actual use must be determined by a licensed prescribing physician.