Rolip Eze

Description

This combination medicine contains Rosuvastatin, a statin that slows cholesterol production in the liver, and Ezetimibe, which reduces cholesterol absorption in the intestines. Together, they work synergistically to lower LDL cholesterol and triglycerides while raising HDL cholesterol. By reducing cholesterol buildup in the arteries, this therapy helps decrease the risk of cardiovascular complications such as heart attack, stroke, and blocked arteries. It is particularly useful in patients who require additional cholesterol-lowering beyond what statins alone can achieve.

Uses

• Reduction of LDL cholesterol levels.

• Treatment of primary hyperlipidemia.

• Management of dyslipidemia.

• Cardiovascular risk reduction.

• Patients requiring combination therapy when statin monotherapy is insufficient.

Dosage

To be taken exactly as prescribed by your doctor. Dose depends on the severity of hyperlipidemia and individual patient response.

In Case of Overdose

Overdose may be life-threatening, with risks of muscle breakdown (rhabdomyolysis), kidney damage, or liver dysfunction. Seek immediate medical attention if symptoms such as severe muscle pain, weakness, dark urine, or dizziness occur.

Missed Dose

If a dose is missed, take it as soon as possible. If it is close to the next scheduled dose, skip the missed one. Do not double up doses.

How to Use

Swallow the tablet whole with a glass of water. It can be taken with or without food. Take it at the same time every day for the best results.

When Not to Use

Avoid this medication if you have:

• Known allergy to Ezetimibe, Rosuvastatin, or other statins.

• Active liver disease or persistent elevated liver enzymes.

• Pregnancy or breastfeeding.

• Severe lung disease with muscle weakness (rare statin-related complication).

Side Effects

• Common: Nausea, constipation, stomach upset, loss of appetite, mild muscle pain.

• Serious (rare): Severe muscle weakness, rhabdomyolysis, abnormal liver function tests.

Precautions & Warnings

• Inform your doctor if you experience unexplained muscle pain, weakness, or tenderness.

• Regular liver function and lipid profile monitoring is advised during therapy

• Temporary discontinuation may be needed before major surgery.

• Avoid alcohol, as it increases liver strain.

Drug Interactions

May interact with:

• Fusidic acid (risk of severe muscle damage).

• Certain antiviral drugs.

• Medicines for indigestion/antacids (may reduce absorption).

• Anticoagulants (may enhance bleeding risk).

Storage/Disposal

Store in a cool, dry place away from heat and direct sunlight. Keep tightly closed and out of children’s reach. Dispose of expired tablets properly; do not flush down the toilet.

Control Drug

No

Quick Tips

• Take at the same time every day

• Do not crush, chew, or split the tablet

• Combine with a cholesterol-lowering diet and exercise plan for maximum benefit

Doctor’s Review

Dr. Hassan Raza (Cardiologist):
“Rosuvastatin and Ezetimibe together provide a strong cholesterol-lowering effect. This combination is especially beneficial in patients with stubbornly high LDL cholesterol despite statin use. While generally safe and effective, liver function and muscle health must be monitored closely. Patients are advised to maintain healthy lifestyle practices alongside medication for best long-term cardiovascular protection.”

Disclaimer

This information is provided for educational purposes only and should not replace the guidance of a licensed healthcare professional. Always consult your doctor before starting, stopping, or adjusting any medication.