Samerol-N Forte

Description

This medicine combines Orphenadrine Citrate, a muscle relaxant with mild sedative properties, and Paracetamol, a widely used pain reliever and fever reducer. The combination helps ease muscle spasms, reduce pain, and improve comfort in musculoskeletal conditions such as strains, sprains, and back pain.

Ingredients

• Orphenadrine Citrate 35mg.

• Paracetamol 450mg.

Drug Class

• Muscle relaxant (Orphenadrine).

• Analgesic/antipyretic (Paracetamol).

Uses

• Relief of muscle spasms and stiffness.

• Pain management in musculoskeletal injuries (sprains, strains, back pain).

• Supportive treatment in acute muscle conditions and fibromyalgia.

• Temporary relief of aches linked to muscle overuse or tension.

Dosage

• Adults: usually 1 tablet, 2–3 times daily (as directed by a doctor).

• Maximum dose must not exceed prescribed limits to avoid liver damage from paracetamol.

• Swallow whole with water, with or without food.

• Missed dose: take when remembered; skip if near next scheduled dose. Do not double.

Side Effects

• Drowsiness, dizziness, headache.

• Dry mouth, constipation.

• Nausea, abdominal discomfort.

• Blurred vision, skin rash.

• Rare: liver problems (jaundice, nausea, dark urine).

Precautions & Warnings

• Use with caution in patients with liver or kidney disease.

• Avoid alcohol — raises risk of liver damage and sedation.

• Not recommended in patients with glaucoma, urinary retention, or myasthenia gravis.

• Should not be given to children under 12 unless advised by a doctor.

• May cause drowsiness — avoid driving or using heavy machinery.

Contraindications

Do not use if:

• Severe liver impairment or active liver disease.

• History of alcohol abuse.

• Glaucoma or urinary retention.

• Known allergy to orphenadrine, paracetamol, or related medicines.

• Acute porphyria.

• Children under 12 years (unless prescribed).

Interactions

• Alcohol, sedatives, or narcotics: increase drowsiness and risk of side effects.

• Other hepatotoxic drugs (certain antifungals, anticonvulsants): raise risk of liver injury.

• Anticholinergic medicines: may worsen dry mouth, blurred vision, urinary problems.

• High-fat meals: may delay absorption.

Storage

• Store in a cool, dry place (18–25°C).

• Protect from light and moisture.

• Keep away from children.

• Dispose of expired tablets safely — do not flush in toilets or drains.

Quick Tips

• Take only the prescribed dose; do not exceed limits.

• Avoid alcohol completely during use.

• If drowsy, do not drive or operate machines.

• Taking with food may reduce stomach upset.

Doctor’s Review

Dr. Imran Siddiqui – Consultant Orthopedic Specialist
“This combination of orphenadrine and paracetamol is recognized in clinical practice for easing muscle spasms and pain from musculoskeletal conditions. Orphenadrine helps relax muscles through its effect on the nervous system, while paracetamol provides additional pain relief. It is generally considered for short-term use. Monitoring liver function and avoiding alcohol are important for safe treatment.”

Disclaimer

This profile is for educational purposes only. It is not medical advice or a prescription. Always consult a qualified healthcare professional before starting or stopping any medication.