Tariflox 200mg

Description

Ofloxacin is a fluoroquinolone-class antibacterial agent with broad-spectrum activity. It acts by inhibiting bacterial DNA gyrase, interfering with DNA replication, transcription, and repair, resulting in bactericidal action.

Drug Class

Fluoroquinolone Antibiotic

Dosage Form

Oral Film-Coated Tablet

Common Approved Uses / Indications

As per data, indicated for infections caused by Ofloxacin-sensitive bacteria, including:

• Respiratory tract infections (acute or chronic bronchitis, pneumonia).

• ENT infections (ear, nose, throat).

• Skin and soft tissue infections.

• Urinary tract infections (upper and lower), including uncomplicated gonorrhea.

• Bone and joint infections.

• Abdominal and pelvic infections.

• Gastrointestinal bacterial infections.

• Prophylaxis of infection in immunocompromised states.

Dosage

• Usual adult range: 200mg to 800mg daily in 1–2 divided doses, depending on severity and infection type.

• Duration typically 3 to 10 days, but varies by indication.

• Dose adjustment required in renal impairment.

Administration: Swallowed whole with liquid, with or without food.

When Not to Use

• Known hypersensitivity to Ofloxacin or other quinolone antibiotics.

• Use in individuals under 18 years, pregnant, or lactating is not established.

Side Effects

Gastrointestinal: Nausea, stomach upset, abdominal pain, diarrhea, loss of appetite.
Neurological: Headache, dizziness, sleep disturbances, rarely convulsions or sensory changes.
Skin / Allergy: Rash, itching, photosensitivity, swelling of face or airway (rare).
Hematologic: Rare reduction in blood cell counts.
Hepatic / Renal: Rare increases in liver enzymes or creatinine.
Musculoskeletal: Joint or tendon pain; very rare cases of tendon rupture.
Others: Increased heart rate, weakness.

Precautions & Warnings

• Hydration required to avoid crystalluria.

• Avoid excessive sunlight/UV exposure due to phototoxicity risk.

• Use with caution in renal or hepatic impairment.

• May lower seizure threshold in susceptible individuals.

• May affect blood glucose when used with antidiabetic agents.

• May impair alertness — caution with driving or machinery.

Drug Interactions

• Reduced absorption when taken with antacids, sucralfate, iron, zinc, calcium/magnesium products — separate by at least 2 hours.

• May elevate theophylline levels — monitor if used concurrently.

• Increased seizure risk with NSAIDs.

• May potentiate hypoglycemic agents (insulin, sulfonylureas).

Storage & Handling

• Store below 30°C, protected from heat, light, and moisture.

• Keep out of reach of children.

• For disposal, follow local pharmaceutical waste protocols.

Control Status

Non-Controlled Prescription Drug.

Quick Notes

• Swallow whole — do not crush.

• Avoid tanning beds and prolonged sun exposure.

• Stop use if rash or tendon pain occurs.