Introduction
Typhim Vi is a prescription vaccine used to prevent typhoid fever caused by Salmonella typhi. It is approved for adults and children aged 2 years and above. It is commonly recommended for travelers to high-risk regions, food handlers, healthcare workers, and people living in areas with poor sanitation. One intramuscular injection develops immunity within approximately 14 days and protection lasts up to three years.
Primary Uses
Prevention of typhoid fever in individuals at risk of exposure to Salmonella typhi.
Indications
Vaccination is recommended for adults and children aged 2 years and older who are likely to be exposed to typhoid through travel, contaminated food or water, or close contact with carriers.
Dosage and Administration
Adults and children (2+ years): Single 0.5 mL dose administered intramuscularly in the deltoid or thigh muscle.
Do not inject intravenously or into the buttocks.
Vaccination should be given at least 14 days prior to possible exposure.
Revaccination is recommended every three years if the risk continues.
Side Effects
Local reactions such as pain, redness, or swelling at the injection site.
Mild systemic symptoms such as fever, fatigue, headache, or muscle pain.
Rare gastrointestinal symptoms such as nausea or abdominal discomfort.
Very rare risk of allergic reactions including rash or anaphylaxis.
Warnings
Does not protect against Salmonella paratyphi or non-typhoidal strains.
Immune response may be weaker in immunocompromised individuals.
Do not administer intravenously.
Syncope (fainting) may occur; vaccinate under supervision.
Use caution in individuals with bleeding disorders or low platelet count.
Contraindications
Postpone vaccination in case of active fever or acute illness.
Avoid in individuals with known hypersensitivity to vaccine components including phenol, formaldehyde residues, or casein derivatives.
Storage
Store between 2°C and 8°C (refrigerated).
Do not freeze.
Protect from direct light.
Doctor’s Overview
According to infectious disease specialists, Typhim Vi is an effective preventive option for individuals at risk of typhoid exposure. A single dose offers coverage for up to three years. It is generally safe with mild and short-lived side effects, but administration should be supervised in individuals with a history of severe allergies or bleeding disorders.
Disclaimer
This is general medical information and not a substitute for professional advice. Always consult a doctor before vaccination, especially in case of allergies, pregnancy, or chronic illness.

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