X-Plended (10mg) 10 Tablets

Manufacturer: PharmEvo (Pvt.) Ltd.
Generic Name: Rosuvastatin

X-Plended contains Rosuvastatin 10mg, a statin medication belonging to the HMG-CoA reductase inhibitor class. It works by reducing the liver’s production of cholesterol and improving the body’s ability to remove low-density lipoprotein (LDL, or “bad cholesterol”) from the blood. This helps prevent cholesterol build-up in arteries, reducing the risk of heart disease and stroke.

• Rosuvastatin 10mg

Uses

Rosuvastatin is prescribed for:

• Lowering LDL cholesterol and triglycerides

• Increasing HDL cholesterol (“good cholesterol”)

• Treatment of hyperlipidemia and hypertriglyceridemia

• Familial hypercholesterolemia (genetic high cholesterol disorder)

• Prevention of cardiovascular disease, including heart attack and stroke

Dosage

• Taken once daily as prescribed by a physician

• Dosage may vary depending on cholesterol levels and patient profile

In Case of Overdose

Overdose may lead to serious complications, including muscle damage and liver problems. Immediate medical care is required.

Missed Dose

If a dose is missed, take it as soon as remembered. If it is close to the next scheduled dose, skip the missed dose. Do not double.

How to Use

• Swallow whole with a glass of water

• Can be taken with or without food

• Take consistently at the same time each day

When Not to Use

X-Plended should not be used in:

• Patients with hypersensitivity to rosuvastatin or other statins

• Pregnant or breastfeeding women

• Patients with active liver disease or unexplained persistent liver enzyme elevation

• Patients with severe lung disease or uncontrolled muscle disorders

Side Effects

Possible side effects include:

• Nausea, stomach upset, constipation

• Loss of appetite

• Headache or dizziness

• Muscle pain, tenderness, or weakness

• Rare: severe muscle damage (rhabdomyolysis)

Precautions & Warnings

• Report any unexplained muscle pain or weakness immediately

• Regular monitoring of liver function tests is advised

• Patients undergoing major surgery may need temporary discontinuation

• Avoid excessive alcohol intake

• Use cautiously in patients with kidney or thyroid problems

Drug Interactions

• Fusidic acid (may increase risk of muscle toxicity)

• Certain antivirals (e.g., protease inhibitors)

• Medicines for indigestion (antacids containing aluminum/magnesium)

• Anticoagulants (blood-thinners like warfarin)

Storage / Disposal

• Store at room temperature, away from heat, moisture, and direct sunlight

• Keep out of reach of children

• Do not use after expiry date

Quick Tips

• Do not crush, chew, or split the tablet

• Combine with a low-cholesterol diet and lifestyle changes for best results

Doctor’s Review

Dr. Imran Siddiqui, Consultant Cardiologist
“Rosuvastatin (X-Plended) is one of the most effective statins for lowering LDL cholesterol and reducing cardiovascular risk. It is well tolerated by most patients but requires monitoring for liver function and muscle-related side effects. For patients with high cholesterol or a strong family history of heart disease, it can play an important role in long-term prevention.”

Disclaimer

This information is provided for educational purposes only. It describes the general product profile of X-Plended (Rosuvastatin) in Pakistan. It is not a medical prescription. Always consult a qualified doctor or pharmacist before starting or changing any cholesterol-lowering medication.