Xovat

Introduction

Xovat 5mg tablets step in when cholesterol levels start acting up — like when routine nihari breakfasts or late-night paratha sessions finally begin showing up in blood reports. Each strip has 10 tablets of Rosuvastatin 5mg, a statin used widely in Pakistan to control high cholesterol and protect the heart from long-term damage. It’s a small, easy-to-take tablet usually taken once a day, often at night, depending on doctor guidance.

Primary Uses

Xovat 5mg is generally used for:

• High cholesterol (Hyperlipidemia).

• Mixed dyslipidemia — when both LDL (bad cholesterol) and triglycerides are high.

• Raising HDL (good cholesterol) as part of long-term heart protection.

How It Works

Rosuvastatin mainly works inside the liver, where most cholesterol is made. It blocks the enzyme responsible for cholesterol production, reduces LDL (“bad”) cholesterol in the blood, and increases the breakdown of existing cholesterol by increasing LDL receptors. It also lowers VLDL and triglyceride levels, helping prevent artery blockage in the long run.

Side Effects

Some people may notice:

• Headache or dizziness.

• Constipation or stomach discomfort.

• Muscle pain or weakness (myalgia).

• Nausea or abdominal cramps.

• Skin rash or itching in sensitive users.

• Rare but serious: intense muscle breakdown (rhabdomyolysis), pancreatitis, or allergic swelling.

If muscle pain feels unusual or persists, doctors usually investigate further.

Drug Interactions

Caution is generally observed when Xovat is taken with:

• Blood thinners (Coumarin anticoagulants).

• Gemfibrozil or Niacin (used for lipid control).

• Antacid suspensions with aluminium or magnesium — may reduce absorption if taken together.

When Not to Use

Avoid Xovat 5mg in:

• Allergy to Rosuvastatin or similar statins.

• Active liver disease or unexplained elevated liver enzymes (ALT/AST).

• Pregnancy and breastfeeding — statins are avoided in these phases.

Precautions & Warnings

• Doctors usually start from a lower dose and increase gradually, depending on response.

• Regular monitoring of liver function and kidney profile is routine during therapy.

• Caution in people with liver history, alcohol intake, thyroid imbalance, muscle disorders, or previous statin intolerance.

• If persistent protein or blood appears in urine tests, dose reassessment is considered.

Doctor’s Overview

Dr. Sameer Khan (Cardiology Registrar, Karachi):
“Rosuvastatin 5mg, like Xovat, is commonly chosen as a starting statin dose in Pakistan for cholesterol control. It offers strong LDL reduction with relatively low daily dosing. Muscle discomfort or liver enzyme changes are uncommon but monitored during therapy.”

Storage

• Store at room temperature, away from heat and direct light

• Keep sealed and out of reach of children

Disclaimer: This is a general information profile based on standard DRAP-approved clinical use. It is not a prescription. Always consult a healthcare professional for personal treatment decisions.