Zetrine

Description

Cetirizine is a second-generation antihistamine that works by blocking the action of histamine, a chemical released during allergic reactions. By targeting H1 receptors, it prevents symptoms such as sneezing, itching, runny nose, watery eyes, and skin irritation. Unlike older antihistamines, Cetirizine causes less drowsiness and is suitable for both short-term and long-term allergy management.

Ingredients

Cetirizine (concentration varies per brand – typically 5mg/5mL)

Drug Class

Second-generation Antihistamine

Dosage Form

Syrup / Suspension

Uses

Cetirizine Syrup is commonly used for:

• Seasonal allergic rhinitis (sneezing, runny or itchy nose, watery eyes)

• Perennial allergic rhinitis (year-round allergies)

• Allergic conjunctivitis (eye redness and itching)

• Urticaria (hives) and skin allergies

• Itching or swelling caused by insect bites

• General allergic reactions and hay fever symptoms

Dosage

• Adults & Children 12+ years: 10mg (10mL) once daily

• Children 6–12 years: 5mg (5mL) once daily

• Children 2–5 years: 2.5mg (2.5mL) once daily

• Children under 2 years: Use only as advised by a doctor

Overdose

May cause excessive drowsiness, fast heartbeat, headache, or dry mouth. Seek immediate medical attention.

Missed Dose

Take as soon as remembered. Skip if near the next dose. Do not double the dose.

How to Use

Shake well before use. Measure with a dosing spoon or syringe. Take once daily, with or without food.

When Not to Use

• Allergy to Cetirizine or related antihistamines

• Severe kidney impairment without medical supervision

• Concurrent alcohol or sedative abuse

Side Effects

• Drowsiness

• Dry mouth

• Headache

• Nausea or stomach discomfort

• Fatigue or dizziness

• Rash (rare)

Precautions & Warnings

• Use with caution in kidney patients

• Avoid alcohol and sedatives

• May cause drowsiness in some users—avoid driving if affected

• Pregnant or breastfeeding women should consult a doctor

Drug Interactions

• Alcohol and sedatives increase drowsiness

• Concomitant use with other antihistamines may enhance sedation

• Theophylline may slow Cetirizine clearance

Food Interactions

No major interactions. Can be taken with or without food. Avoid alcohol.

Storage / Disposal

Store at room temperature away from sunlight and moisture. Keep tightly closed and out of reach of children. Dispose as per pharmacist guidance.

Quick Tips

• Take at the same time daily

• Avoid driving if it makes you sleepy

• Complete the prescribed duration even if symptoms improve

• Shake well before each dose

Doctor’s Review — Dr. Imran Siddiqui, Consultant Internal Medicine

Cetirizine is a reliable and well-tolerated antihistamine for both adults and children. It provides fast relief from most allergic symptoms without significant sedation. However, patients should avoid overdosing and remain cautious when combining it with alcohol or sedatives.

Disclaimer

This information is for educational purposes only and must not replace medical advice. Always consult your physician before starting or changing any medication.