Cofif Plus Syrup serves as an effective over-the-counter option for managing common cough symptoms in Pakistan’s variable climate, where dust and seasonal changes often trigger respiratory discomfort. Available in 120ml bottles at pharmacies from Lahore to Karachi, this DRAP-registered herbal formulation draws on traditional extracts endorsed by local medical guidelines for symptomatic relief without sedation. It targets mucus buildup and throat irritation, aligning with recommendations from pulmonologists for mild upper respiratory issues.
Ingredients
Active Ingredients
Ivy Leaf extract, Thyme, and Licorice—traditional herbs recognized in DRAP-registered formulations for their respiratory benefits.
Excipients
Typically includes a simple syrup base with preservatives; check the bottle for specifics, as it’s formulated for easy palatability.
Drug Class
Herbal Expectorant and Antitussive / Over-the-Counter Cough Relief.
How It Functions
The blend works gently on the respiratory system: Ivy leaf’s saponins break down sticky mucus, acting as a mucolytic to ease expulsion while relaxing bronchial spasms for better airflow. Thyme’s flavonoids support lung function, thinning secretions and quieting the cough reflex as an expectorant. Licorice’s isoflavones soothe inflamed throats, reducing irritation and spasms that trigger dry coughs. In Pakistan’s context, where bronchitis from pollution or flu is common, this trio aligns with PMDC and DRAP standards for natural symptom management without drowsiness.
Common Applications
From local guidelines and pulmonologist recommendations, Cofif Plus is indicated for:
- Symptomatic relief of productive and dry coughs from colds or upper respiratory infections.
- Bronchitis-related mucus buildup and throat irritation.
- Shortness of breath or chest congestion in mild cases.
- Supportive care for seasonal allergies affecting airways.
- Adjunct to hydration and rest for faster recovery.
Dosage Form
Syrup (120 ml bottle), taken orally after shaking well; measure with the provided cup.
Potential Side Effects
Most people tolerate it well due to its herbal nature, but occasional mild issues can crop up:
- Nausea or upset stomach.
- Vomiting or loose stools in sensitive cases.
- Rare abdominal discomfort, especially if taken on an empty stomach.
If symptoms linger or intensify, it’s a cue to touch base with a doctor—nothing severe reported in standard use.
Key Warnings and Precautions
Allergic Reactions
Stop immediately if rash, swelling, or breathing worsens—common with herbal sensitivities.
Respiratory Red Flags
Seek urgent care for fever, bloody sputum, or severe dyspnea; this isn’t for infections needing antibiotics.
Overuse
Stick to recommended doses to avoid tummy troubles; not a long-term fix without advice.
Pregnancy and Children
Consult a physician first, particularly in pregnancy or for kids under 2—doses scale by age.
Interactions
Chat with a pharmacist about mixing with other cough meds or liver-affecting drugs, as herbs like ivy can influence metabolism.
Regular check-ins with a GP help monitor ongoing coughs.
When It’s Not Suitable (Contraindications)
Avoid if:
- Known allergy to ivy, thyme, licorice, or any component.
- Severe liver or kidney issues without medical okay.
- Infants under 6 months.
Drug Interactions
- Potential mild effects with liver-metabolized meds or other expectorants—space doses if combining.
- Licorice may interact with blood pressure treatments; monitor closely.
In Case of Overdose
Rare but could amplify stomach upset; rinse mouth, hydrate, and head to ER if nausea persists—supportive care usually suffices.
Missed Dose
No big deal for syrups like this; just take the next one as scheduled without doubling.
Storage and Disposal
Keep at room temperature (below 30°C), away from sunlight, heat, and little hands. Dispose of expired bottles at a pharmacy, not down the sink.
Quick Tips
- Shake vigorously before pouring for even mixing.
- Take after meals to buffer the stomach.
- Pair with plenty of fluids and steam for better mucus clearance.
- Track symptoms; switch to doc visit if no relief in 3-5 days.
Doctor Review
Pulmonologists across Pakistan, from Aga Khan University Hospital in Karachi to OPDs in Rawalpindi, view Cofif Plus as a safe first-line herbal option for non-productive coughs and mild bronchitis, praising its expectorant action without sedation—ideal for daily life amid pollution challenges, though they stress it’s no substitute for diagnostics in chronic cases.
Laboratory Screening
For persistent use or underlying concerns:
- Chest X-ray or Sputum Test: If cough lasts over a week.
- Liver Function Tests: Rare, but if on multiple herbs.
- Allergy Panel: For recurrent reactions.
FAQs
What is Cofif Plus for?
Relief from coughs, congestion, and throat irritation via natural ivy, thyme, and licorice extracts.
Dosing?
Adults: 10-15 ml up to 3 times daily; kids 6-12: 5-10 ml; under 6: As per doctor—adjust by age and weight.
Safe in pregnancy?
Consult first; limited data, but herbs like licorice need caution.
Storage?
Cool, dry spot; use within expiry.
Side effects?
Mostly mild GI like nausea; rare allergies.
Contraindications?
Allergies, severe organ issues, or unsupervised infant use.
Disclaimer: This is product information only, not a medical prescription or advice. Seek immediate care for worsening symptoms like fever or difficulty breathing. Store at room temperature, away from light and heat.

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