Ceclor

Description

Cefaclor, the key component in this 250mg syrup/suspension, belongs to the second-generation cephalosporin antibiotics. It achieves its bactericidal action by interfering with bacterial cell wall synthesis, specifically by attaching to penicillin-binding proteins (PBPs) in vulnerable bacteria. This prevents the cross-linking of peptidoglycan chains, compromising the cell wall’s strength and resulting in bacterial lysis and elimination. The effect targets bacteria exclusively, as human cells lack cell walls and remain unaffected.

Ingredients

• Cefaclor 250 mg.

Drug Class

• Cephalosporin antibiotic.

Dosage Form

• Suspension.

Uses

Cefaclor 250mg Syrup/Suspension is indicated for:

• Addressing bacterial infections including those of the ear, skin, and respiratory tract.
• Handling acute bacterial flare-ups in chronic bronchitis patients.
• Treating pneumonia from susceptible organisms.
• Alleviating urinary tract infection (UTI) symptoms.
• Managing infections in immunocompromised individuals.
• Preventing post-surgical infections or those in severe burn cases.
• Early-stage Lyme disease treatment.

Dosage

Dosage should always be determined by a doctor’s advice; the following information is provided as supportive reference for informational purposes only.

In Case of Overdose

Overdose may lead to nausea, vomiting, diarrhea, and abdominal discomfort. Immediate medical care is recommended, where interventions like inducing vomiting or using activated charcoal might be employed to limit absorption.

Missed Dose

Take the missed dose upon recollection, but if nearing the next dose, omit it and resume the schedule. Avoid doubling doses to compensate, as it heightens side effect risks. For multiple missed doses, seek healthcare provider advice.

How to Use

Shake the bottle thoroughly before measuring the exact dose with a provided spoon or syringe. Consume orally as directed, usually twice daily, with or without meals, and finish the entire prescribed course.

When Not to Use

Avoid in:

• Known allergies to cefaclor or other cephalosporins.
• History of severe penicillin reactions due to potential cross-sensitivity.
• Severe renal impairment without dose modification.
• Gastrointestinal conditions like colitis or intestinal disorders.
• Infections from resistant bacteria.
• Infants under one month, as safety data is lacking.
• History of seizures or seizure-risk conditions.

Side Effects

Potential adverse effects include:

• Nausea and vomiting.
• Diarrhea.
• Abdominal pain.
• Skin rash or itching.
• Headache.
• Dizziness.
• Vaginal yeast infections.
• Fatigue.

Precautions & Warnings

• Avoid if allergic to cefaclor or penicillin-based antibiotics.
• Complete the full treatment to curb resistance development.
• Shake well prior to each administration for consistency.
• Use a precise measuring tool for dosing.
• Diarrhea may occur; seek advice if severe.
• Dose adjustments needed for kidney or liver issues.
• Inform providers of use before lab tests, as it may interfere.
• Store securely away from children and pets at room temperature.

Drug Interactions

• Probenecid may elevate cefaclor levels by slowing excretion.
• Combined with nephrotoxic agents (e.g., aminoglycosides, diuretics) could raise kidney damage risk.
• May lessen oral contraceptive efficacy; use backup methods.
• Can cause false positives in urine galactose tests.
• Antacids with aluminum, magnesium, or calcium might hinder absorption.
• Could impact live bacterial vaccines like typhoid.
• Monitor prothrombin time with anticoagulants such as warfarin.

Food Interactions

• Can be taken regardless of meals, though food may ease stomach issues.
• Steer clear of alcohol to avoid amplified side effects or reduced efficacy.
• High-fat foods might slow absorption.
• Grapefruit products: Use cautiously, though no confirmed interaction.
• Dairy: Check with provider on timing, as it may affect absorption.
• Limit caffeine to reduce risks of nervousness or insomnia.
• Avoid natural licorice due to potential cardiac effects.
• Seek personalized dietary guidance from a healthcare professional.

Storage/Disposal

Keep in a cool, dry area at room temperature, shielded from sunlight and humidity. Seal tightly in the original bottle. Avoid bathrooms or heat sources. Do not use past expiration; dispose safely without flushing—consult a pharmacist for proper methods. Store out of children’s reach.

Control Drug

No

Quick Tips

• Adhere to prescribed duration and amount.
• Shake bottle well before use.
• Measure accurately with a clean device.
• For tablets (if applicable), swallow whole without splitting.
• Store away from light and moisture; do not freeze.
• Discard expired portions.
• Track health and report persistent issues to a doctor.

Doctor’s Review

Dr. Sara Iqbal (Infectious Disease Specialist): “Cefaclor 250mg Syrup/Suspension operates as a cephalosporin antibiotic that targets bacterial cell wall formation by inhibiting key proteins, leading to bacterial breakdown, and is useful for various infection types without affecting human cells.”

Disclaimer

This product profile is provided for informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. Always consult a qualified healthcare professional before starting, stopping, or changing any medication regimen. The information herein should not be used as a substitute for professional medical guidance.