Aldactazide 25 mg is a combination medication that contains spironolactone and hydrochlorothiazide. It is primarily used to treat conditions like hypertension (high blood pressure) and edema (fluid retention) associated with heart failure, liver cirrhosis, or certain kidney disorders.
Key Features:
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Active Ingredients:
- Spironolactone: A potassium-sparing diuretic that prevents the body from absorbing too much salt while keeping potassium levels from getting too low.
- Hydrochlorothiazide: A thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.
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Indications:
- Hypertension (High Blood Pressure): Helps lower blood pressure, reducing the risk of strokes, heart attacks, and kidney problems.
- Edema: Effective in reducing fluid retention in conditions like congestive heart failure, liver cirrhosis, and nephrotic syndrome.
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Mechanism of Action:
- Spironolactone works by blocking aldosterone, a hormone that can cause the body to retain sodium and water. By blocking this hormone, spironolactone allows the kidneys to eliminate excess sodium and water while retaining potassium.
- Hydrochlorothiazide increases urine production by preventing the kidneys from absorbing excess salts, leading to a reduction in blood volume and pressure.
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Dosage and Administration: Aldactazide 25 mg is typically taken once daily, with or without food. The exact dosage and frequency depend on the patient’s condition and response to treatment. It is important to follow the prescribing doctor’s instructions and not to exceed the recommended dose.
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Side Effects: Common side effects may include dizziness, headache, dehydration, electrolyte imbalance, and gastrointestinal issues like nausea or vomiting. More serious side effects can include hyperkalemia (high potassium levels), significant electrolyte imbalances, and kidney dysfunction, requiring immediate medical attention.
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Precautions: Patients with conditions such as kidney disease, high potassium levels, or those taking potassium supplements should use this medication with caution. Regular monitoring of blood pressure, kidney function, and electrolyte levels is often necessary during treatment.
Aldactazide 25 mg is an effective treatment option for managing hypertension and edema, especially in patients who may require a combination of diuretics for better control of their condition. It is important to use this medication under the supervision of a healthcare provider to ensure safety and efficacy.
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