Bezone

Brand: Medisave
Generic Name: Cefoperazone 1000mg + Sulbactam 1000mg
Drug Class: Cephalosporin Antibiotic + Beta-lactamase Inhibitor

Introduction

Bezone injection is a combination of two powerful antibiotics, Cefoperazone and Sulbactam. Cefoperazone belongs to the cephalosporin family, while Sulbactam helps in overcoming bacterial resistance, making the treatment more effective. Because of this combination, Bezone is often prescribed by doctors in Pakistan for infections that do not respond well to regular antibiotics.

It is commonly used for serious bacterial infections of the lungs, skin, abdomen, urinary system, blood, and female reproductive organs. One important benefit is that it works against pseudomonas bacteria, which are usually resistant to most other medicines.

When Doctors Prescribe Bezone

Pakistani doctors may recommend this injection in conditions such as:

• Pneumonia or other chest infections

• Infections inside the abdomen, including peritonitis

• Blood infections (septicemia)

• Skin and wound infections

• Pelvic infections and post-delivery uterine infections

• Severe urinary tract infections

• Infections acquired after surgery or in hospitals

How It Is Given

This injection is not self-administered. It must be given by a doctor or trained nurse. The medicine is usually injected either into a vein (IV) over 15–60 minutes or directly into a muscle (IM). The exact dose depends on your age, body weight, and the severity of infection. Patients with kidney or liver problems may require dose adjustments.

Possible Side Effects

Like all antibiotics, Bezone can cause some unwanted effects. The most commonly reported ones include:

• Rash or mild allergic reactions

• Diarrhea

• Pain, redness, or swelling at the injection site

• Temporary changes in liver enzymes or blood counts

• Rarely, a drop in white blood cells or hemoglobin

 If you develop persistent diarrhea, jaundice (yellowing of skin/eyes), breathing difficulty, or a widespread rash, stop using it and seek medical help immediately.

Warnings & Precautions

• Pregnancy: Only to be used if the doctor considers it essential.

• Breastfeeding: Small amounts may pass in breast milk; ask your doctor before use.

• Liver/Kidney Patients: May require dose adjustments.

• Alcohol: Strictly avoid during treatment, as it can cause severe reactions like flushing, nausea, vomiting, or a rapid heartbeat.

• Colitis patients: Should use carefully, as the drug may worsen bowel inflammation.

• Long-term use increases the risk of secondary (super) infections.

Contraindications

Do not use Bezone if you have:

• A known allergy to Cefoperazone, Sulbactam, cephalosporins, or penicillins

• A history of severe antibiotic-related colitis

Frequently Asked Questions

Can Bezone treat resistant infections?
Yes, it is one of the few antibiotics effective against pseudomonas, a bacteria resistant to most drugs.

Does the injection hurt?
Mild pain or swelling at the injection site is common. Using a cold pack can ease it.

Can I drink alcohol while taking this injection?
No. Alcohol and Bezone together can cause very unpleasant reactions, so it must be avoided.

When will I start feeling better?
Most patients notice improvement within a few days, but the full prescribed course must be completed to avoid relapse.

Can I use it at home without a doctor?
No. This injection should only be given under medical supervision.

Doctor’s Opinion

Dr. Ayesha Malik, Infectious Disease Specialist (Pakistan): Bezone is an antibiotic often used in serious abdominal and hospital-acquired infections. It is known to work well when some other antibiotics do not. Using it correctly and completing the course is important for best results.

Storage

• Store in a cool, dry place at room temperature

• Keep away from direct sunlight and heat

• Always keep out of reach of children

• Do not use expired vials

Disclaimer

This product information is provided only for educational purposes. It should not be treated as a substitute for a doctor’s advice. Bezone injection must be used under the supervision of a qualified healthcare professional. Always follow your doctor’s instructions regarding dosage, duration, and possible interactions.