Diabold 1mg

Description
Diabold contains Glimepiride, an oral sulfonylurea-class antidiabetic agent. It primarily lowers blood glucose by stimulating pancreatic beta cells to increase insulin secretion and enhancing cellular response to insulin. Long-term glycemic effects may involve additional metabolic pathways.

Ingredients (Generic Name)
Glimepiride

Drug Class
Sulfonylurea (Oral Antidiabetic Agent)

Dosage Form
Oral Tablet

Requires Prescription
Yes

Uses / Indications
Adjunct to diet and exercise for improving glycemic control in adults with:

• Type 2 Diabetes Mellitus.

Not indicated for:

• Type 1 diabetes mellitus.

• Diabetic ketoacidosis.

Dosage
Glimepiride — dose is individualized based on clinical response and blood glucose monitoring.

In Case of Overdose
Overdose may result in prolonged hypoglycemia. Immediate carbohydrate intake and medical supervision are generally required.

Missed Dose
Take as soon as remembered unless it is near the next dose. Do not double the dose.

How to Use
Administer orally with breakfast or the first main meal of the day. Swallow whole with water.

When Not to Use

• Known hypersensitivity to Glimepiride or other sulfonylureas.

• Patients requiring insulin therapy.

• History of diabetic ketoacidosis.

Side Effects

Common or reported side effects include:

• Metabolic: Hypoglycemia (most frequent).

• Neurological: Dizziness, headache, asthenia.

• Gastrointestinal: Nausea, vomiting, abdominal pain, diarrhea.

• Hepatic: Rare elevation of liver enzymes.

• Dermatologic: Rash, pruritus, erythema, urticaria (rare).

Precautions & Warnings

• Risk of hypoglycemia — higher in elderly, renal impairment, or with missed meals

• Caution in G6PD deficiency — risk of hemolytic anemia

• Cardiovascular risk — sulfonylureas have been associated with increased mortality in long-term data

• Hypersensitivity reactions — rare reports of angioedema and Stevens-Johnson Syndrome

Drug Interactions

Potential interactions with:

• Potentiators of hypoglycemia: Salicylates, sulfonamides, chloramphenicol, coumarins, MAO inhibitors, beta-blockers, probenecid

• Reducing effect: Thiazide diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid

Food Interactions
Hypoglycemia risk increases with delayed meals or low caloric intake. Consistent meal timing is essential.

Storage / Disposal
Store at room temperature away from moisture, light, and heat. Keep out of reach of children.

Control Drug
No

Quick Tips

• Take with food to reduce hypoglycemia risk.

• Monitor blood glucose regularly.

• Recognize early signs of low blood sugar (sweating, tremors, palpitations).

Doctor’s Note (Neutral Review)
— Reviewed by Dr. Rahim Siddiqui, Consultant Endocrinologist

“Glimepiride remains widely used in type 2 diabetes management, but hypoglycemia precaution is essential, especially in older or renally impaired individuals.”

Disclaimer
This information is for reference purposes only and should not replace the advice of a licensed healthcare professional. Treatment must be based on individual clinical judgment.