Fosfomycin is a broad-spectrum antibiotic used to treat bacterial infections, particularly urinary tract infections (UTIs) and infections caused by resistant organisms. It works by interfering with bacterial cell wall synthesis, preventing bacteria from multiplying and allowing the body’s immune system to clear the infection. Fosfomycin is not effective against viral infections such as the flu or common cold.
Primary Uses
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Treatment of urinary tract infections (UTIs)
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Management of infections caused by multi-drug resistant bacteria
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Alternative therapy for patients allergic to other antibiotics
Indications
Fosfomycin IV Injection may be prescribed for:
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Acute cystitis (simple bladder infection)
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Complicated or resistant urinary tract infections
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Other infections where the causative bacteria are known to be sensitive to fosfomycin
Side Effects
Some patients may experience:
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Nausea, vomiting, or diarrhea
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Headache or dizziness
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Rash or skin irritation
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Fatigue or mild fever
Serious but rare effects include:
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Allergic reaction (swelling, itching, breathing difficulty)
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Worsening of kidney or liver function in vulnerable patients
Warnings
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Pregnancy: Use only if clearly necessary and prescribed by a doctor.
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Lactation: Should be used with caution during breastfeeding.
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Driving: May cause dizziness or blurred vision; avoid driving if these occur.
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Kidney/Liver: Regular monitoring is advised in patients with kidney or liver disease.
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Alcohol: No direct interaction known, but medical advice is recommended before consumption.
Precautions
Use with caution if you have:
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Known allergy to fosfomycin or similar antibiotics
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Kidney problems or a history of recurrent kidney infections
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Liver impairment requiring close monitoring
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Diabetes or phenylketonuria (some formulations may contain sugar/aspartame)
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Ongoing vaccination, especially with live bacterial vaccines (e.g., typhoid)
Contraindications
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Allergy or hypersensitivity to fosfomycin
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Patients unable to tolerate the inactive components in the formulation
Doctor’s Review
“Fosfomycin particularly useful for urinary tract infections that do not respond to routine antibiotics. It offers good coverage against resistant bacteria and is a safe option when used under supervision. Careful monitoring in patients with kidney or liver issues, but overall, it remains an important choice in modern antibiotic therapy, especially as resistance is becoming a bigger challenge.”
— Dr. Hina Qureshi, Infectious Diseases Specialist
FAQS
When should Fosfomycin be taken?
It is usually given on an empty stomach, ideally at bedtime after emptying the bladder (oral). IV administration is done in hospital under supervision.
Is it a daily medicine?
No, Fosfomycin is usually given as a single dose, unless the doctor advises otherwise for complicated infections.
Is it habit-forming?
No, Fosfomycin has no habit-forming properties.
Disclaimer
This content is provided for educational and product knowledge purposes only. It does not serve as a prescription or substitute for professional medical advice. Always consult a qualified doctor before starting or stopping any medicine.
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