Pensulide

Description

Pensulide 100mg Tablet contains Nimesulide, a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, inflammation, and fever. It works by blocking the production of substances (prostaglandins) in the body that cause pain and inflammation. Nimesulide provides fast relief in conditions such as arthritis, muscle pain, dental pain, and postoperative inflammation.

This medicine is commonly prescribed for short-term use in acute pain management and inflammation associated with musculoskeletal or joint conditions.

Primary Uses

• Relief of pain and inflammation.

• Management of osteoarthritis and rheumatoid arthritis.

• Postoperative pain and swelling.

• Dental pain after procedures or extractions.

• Sports injuries, sprains, and strains.

• Ear, nose, and throat (ENT) inflammation.

• Bursitis or tendinitis (inflammation of tendons).

• Thrombophlebitis (vein inflammation with clot).

• Pharyngitis (throat inflammation).

How It Works

Nimesulide works by selectively inhibiting the cyclooxygenase-2 (COX-2) enzyme, which is responsible for the synthesis of prostaglandins — chemical substances that trigger pain, fever, and inflammation. By reducing these prostaglandins, Pensulide helps relieve discomfort, reduce swelling, and improve movement in inflamed joints or tissues.

Dosage and Administration

• Take exactly as prescribed by your doctor.

• Usually taken twice daily (every 12 hours) after meals with water.

• Do not exceed the recommended dose or duration.

• Avoid using for more than 10 consecutive days without medical advice.

• Always follow your healthcare provider’s instructions for best results.

Side Effects

Common Side Effects:

• Nausea or stomach discomfort

• Diarrhea

• Headache or dizziness

• Skin rash or itching

Serious Side Effects (Seek immediate medical attention):

• Severe stomach pain or black stools (signs of ulcer or bleeding).

• Jaundice or yellowing of skin/eyes (possible liver damage).

• Unusual tiredness or swelling in hands/feet.

• Shortness of breath or allergic reactions.

This medicine is known to sometimes cause toxic effects on the stomach lining, especially with long-term use. Always use under supervision.

Warnings and Precautions

• Liver Warning: May cause serious liver damage if used for long periods or in high doses. Avoid use in liver disease.

• Kidney Warning: Use cautiously in patients with kidney impairment, especially elderly individuals.

• Heart Disease: Use carefully in patients with heart failure or fluid retention.

• Avoid alcohol, as it increases the risk of stomach bleeding or liver injury.

• Do not take on an empty stomach — always take after food to reduce gastric irritation.

• Avoid use in children under 12 years unless prescribed.

Pregnancy and Lactation

• Pregnancy: Not safe to use during pregnancy. Consult your doctor for safer alternatives.

• Lactation: Not recommended during breastfeeding, as the drug may pass into breast milk and affect the baby.

Contraindications

Pensulide should not be used in:

• Patients with active peptic ulcers or history of stomach bleeding.

• Moderate to severe liver disease.

• Severe kidney impairment.

• Known allergy to Nimesulide or other NSAIDs.

• Individuals with bleeding disorders or history of drug-induced liver injury.

Drug Interactions

Avoid combining with:

• Other NSAIDs (e.g., ibuprofen, diclofenac).

• Blood thinners (e.g., warfarin).

• Alcohol.

• Corticosteroids.

• Antihypertensive drugs (as they may reduce their effect).

• Medicines affecting liver enzymes.

Always inform your doctor about all medications and supplements you are taking.

Storage Instructions

• Store at room temperature (below 25°C).

• Keep away from heat, moisture, and sunlight.

• Do not store in the bathroom.

• Keep out of reach of children and pets.

Quick Tips

• Take after meals to reduce stomach irritation.

• Avoid long-term use without medical advice.

• Do not drink alcohol while using this medicine.

• Stop taking immediately if you experience yellowing of skin or eyes.

• Stay hydrated and avoid self-medication.

• Consult your doctor if pain persists beyond a few days.

Disclaimer:
This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before using Pensulide or any other medication.