Predmide-P

Composition

Eye Drops:
Each ml contains:

• Sulphacetamide sodium U.S.P. ………………. 100 mg

• Prednisolone acetate U.S.P. …………………….. 2 mg

• Phenylephrine HCl U.S.P. ……………………….. 1.2 mg

With:

• Phenylmercuric nitrate 0.004%

• Antipyrine

• Polysorbate 80

• Edetate disodium

• Sodium phosphate (dibasic)

• Sodium phosphate (monobasic)

• Sodium thiosulphate

• Polyvinyl alcohol 14mg

• Purified water

Eye Ointment:
Each ml contains:

• Sulphacetamide sodium U.S.P. ………………. 100 mg

• Prednisolone acetate U.S.P. …………………… 2.5 mg

With:

• Mineral oil

• White petrolatum

• Lanolin alcohol (Preservative-Free)

Clinical Pharmacology

• Sulphacetamide sodium acts as a bacteriostatic agent against a wide range of gram-positive and gram-negative microorganisms by interfering with folic acid synthesis, which bacteria need for growth.

• Prednisolone acetate is a glucocorticoid that reduces inflammation and treats allergic reactions, especially in conditions like blepharitis.

• Phenylephrine HCl is an alpha-sympathomimetic agent that causes vasoconstriction, helping to reduce swelling and redness in the eye by constricting the engorged blood vessels.

Indications

Predmide-P/Predmide is indicated for:

• Treatment of nonpurulent blepharitis and blepharoconjunctivitis (seborrheal, staphylococcal, allergic).

• Treatment of nonpurulent conjunctivitis (allergic and bacterial).

Contraindications

Predmide-P/Predmide should not be used in:

• Acute herpes simplex (dendritic keratitis) infections.

• Purulent untreated infections.

• Vaccinia, varicella, and most other viral diseases of the cornea and conjunctiva.

• Ocular tuberculosis.

• Fungal diseases of the eye.

• Hypersensitivity to any component of the medication.

Adverse Reactions and Precautions

• Infections: In conditions caused by microorganisms, infection may be masked, enhanced, or activated by the steroid component.

• Intraocular Pressure: Extended use may lead to an increase in intraocular pressure in susceptible individuals. Frequent monitoring of intraocular pressure is recommended.

• Corneal and Scleral Thinning: Long-term use of topical corticosteroids, including in patients with thin corneal or scleral tissue, may increase the risk of perforation.

• Caution in Sulfonamide Sensitivity: Use with caution in patients with a known or suspected sensitivity to sulfonamides.

How to Use

• Apply the eye drops or ointment as prescribed by your doctor.

• For eye drops, instill the prescribed amount into the affected eye(s) as directed, avoiding contact with the dropper tip to prevent contamination.

• For ointment, apply a thin layer to the affected eye as directed.

• Do not exceed the prescribed dose or frequency of use.

• Use regularly at the same time each day for optimal results.

Disclaimer

This content is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting, stopping, or changing any medication.