Prodex

Dexibuprofen turns up in Pakistani clinics for tackling moderate to severe pain, like in osteoarthritis or dental issues, where patients need quick relief without opioids. It’s the active S-enantiomer of ibuprofen, hitting harder on inflammation, and PMDC recognizes it in local pain management, though docs at places like Mayo Hospital Lahore or Aga Khan Karachi stick to short courses to dodge gut risks. This pulls from standard practices here—a 60ml suspension runs about PKR 50—straight info, not a go-ahead without prescription.

Basic Product Details

• Form and Strength: Oral suspension 100mg/5ml or tablets 400mg.
• Packaging: 60ml bottle suspension; tablets in strips of 10-20.
• Pricing: PKR 50-100 for suspension pack—check Dawaai.pk or Servaid for generics.
• Brands in Pakistan: Dexibufen, Seractil equivalents, or PMDC-approved from local firms like Bosch or Nabiqasim.

Ingredients

• Active Ingredient: Dexibuprofen (S-(+)-ibuprofen).
• Excipients: Sorbitol, flavors in suspension; starch binders in tablets—label varies.

Drug Class

Non-Steroidal Anti-Inflammatory Drug (NSAID), COX inhibitor.

How It Functions

Dexibuprofen blocks COX-1 and COX-2 enzymes, slashing prostaglandin production that drives pain, swelling, and fever. In Pakistan’s ortho OPDs, it’s picked for its potency in joint pain over regular ibuprofen, but resistance to long-term use comes from bleed risks.

Common Applications

Local guidelines cover:

• Osteoarthritis or rheumatoid arthritis flares.
• Dysmenorrhea (painful periods).
• Dental pain or post-op aches.
• Musculoskeletal strains—doc decides off symptoms.

Dosage Form

Suspension shaken and taken orally with food; tablets swallowed whole.

Potential Side Effects

Watch for:

• Stomach upset, nausea, or abdominal pain.
• Dizziness, headache, drowsiness.
• Skin rash—stop and report.

Serious from reports: GI bleeding (black stools), heart strain, liver/kidney hits (jaundice, swelling). ER for chest pain or severe allergy.

Key Warnings and Precautions

PMDC flags:

• Gut: Ulcers/bleeds higher in elderly, ulcer history, or alcohol users—take with food, monitor.
• Heart/Kidney/Liver: Avoid or adjust if impaired; check functions.
• Pregnancy/Lactation: Not safe—Category C/D; consult doc.
• Asthma/Allergies: Triggers attacks in sensitive folks.
• Driving: Skip if dizzy.
• Alcohol: Boosts bleed risk—avoid.

Close watch for long-term or high-risk patients like those with hypertension or lupus.

When It’s Not Suitable (Contraindications)

No-go if:

• Hypersensitive to NSAIDs or dexibuprofen.
• Active ulcers, GI bleeding, or recent CABG.
• Severe heart failure or rhinitis/asthma tied to NSAIDs.

Drug Interactions

Tell doc about:

• Antihypertensives—may weaken effect.
• Blood thinners, steroids—bleed up.
• Other NSAIDs—double risk.
• No major food ties, but alcohol worsens gut.

In Case of Overdose

Nausea, vomiting, drowsiness—hospital for supportive care, gastric lavage if early.

Missed Dose

Take ASAP unless near next; skip, no doubles.

Storage and Disposal

Cool dry place (15-30°C), away from light/kids. Pharmacy disposal for leftovers.

Quick Tips

• Doc-prescribed dose only, with meals.
• Read leaflet, report rash or gut pain fast.
• Shortest course to cut risks.

Doctor Review

Ortho specialists in Pakistan favor dexibuprofen for acute joint or dental pain where standard ibuprofen falls short, but pair it with PPIs for GI protection and push alternatives like paracetamol first—resistance patterns make cultures key in chronic cases.

Laboratory Screening

Monitor:

• Liver enzymes, kidney function, CBC for bleeding.
• BP and stool occult blood periodically.

This sketches dexibuprofen’s role in local pain relief—context only, see a pro.

Disclaimer: This is product information only, not a prescription or diagnosis. Consult a qualified Pakistani doctor before using dexibuprofen to ensure it’s safe. Seek immediate care for severe symptoms like bleeding, chest pain, or swelling.