Description
Sert Tablets 50Mg contain sertraline HCl, a selective serotonin reuptake inhibitor (SSRI) that enhances serotonergic activity in the central nervous system by inhibiting serotonin (5-HT) reuptake. This mechanism helps alleviate symptoms of various mental health disorders by improving mood regulation.
Ingredients
- Sertraline HCl 50 mg (per tablet)
Dosage Form
- Tablet
Pack Details
- Prescription: Required
- Pack Size: 1 box containing 1 strip (1 strip = 10 tablets)
- Price: Not specified in provided data
Uses
Sert Tablets 50Mg are indicated for:
- Major depressive disorder (MDD)
- Obsessive-compulsive disorder (OCD)
- Panic disorder (PD)
Dosage
Dosage should always be determined by a doctor’s advice; the following information is provided as supportive reference for informational purposes only. Adjusted based on condition, severity, and patient response.
In Case of Overdose
Overdose may lead to symptoms such as drowsiness, nausea, rapid heartbeat, tremors, or serotonin syndrome (potentially life-threatening). Seek immediate medical attention.
Missed Dose
Take the missed dose as soon as remembered. If it is nearly time for the next dose, skip the missed one and do not double the dose.
How to Use
Administer orally as prescribed, typically once daily, with or without food. Follow the healthcare provider’s instructions for consistent use.
When Not to Use
Avoid in:
- Patients taking MAOIs (e.g., selegiline, tranylcypromine, linezolid, methylene blue) or within 14. days of stopping them, due to serotonin syndrome risk.
- Patients taking pimozide (risk of QT prolongation).
- Known hypersensitivity to sertraline (e.g., anaphylaxis, angioedema).
Side Effects
Common side effects:
- Nausea.
- Diarrhea.
- Insomnia.
- Drowsiness.
- Headache.
- Dry mouth.
Serious side effects:
- Hypersensitivity reactions.
- Serotonin syndrome.
- Increased bleeding risk.
- Suicidal thoughts/behaviors.
- Activation of mania/hypomania.
- Discontinuation syndrome.
- Seizures.
- Angle-closure glaucoma.
- Hyponatremia.
Precautions & Warnings
- Late pregnancy use may increase neonatal risks (e.g., prolonged hospitalization, respiratory support, persistent pulmonary hypertension).
- Monitor for serotonin syndrome, a potentially life-threatening condition.
- Increased bleeding risk with NSAIDs, aspirin, warfarin, or other anticoagulants.
- Hyponatremia risk; monitor sodium levels, especially in elderly or those on diuretics.
- Pregnancy Category: Consult a physician before use.
- Driving: May impair alertness; avoid tasks requiring focus until effects are known.
- Alcohol: Avoid to prevent worsened side effects or interactions.
Drug Interactions
- MAOIs (e.g., selegiline, phenelzine).
- Pimozide.
- Other SSRIs/SNRIs, triptans, tricyclic antidepressants.
- Fentanyl, lithium, tramadol, tryptophan, buspirone, St. John’s Wort.
- Antiplatelets/anticoagulants (e.g., aspirin, warfarin, clopidogrel).
- Propafenone, flecainide, atomoxetine, desipramine.
- Dextromethorphan, metoprolol, nebivolol, perphenazine, thioridazine, tolterodine, venlafaxine.
- Fosphenytoin.
Food Interactions
No significant food interactions; can be taken with or without meals. Avoid alcohol.
Storage/Disposal
Store at room temperature, protected from direct light and heat. Dispose of unused or expired medication per local regulations; do not flush.
FAQs
What is this medication? An SSRI that boosts serotonin levels to treat depression, OCD, and panic disorder.
How does it work? Inhibits serotonin reuptake to enhance mood regulation in the brain.
Can it be used in pregnancy? Effects unclear; consult a doctor due to potential neonatal risks.
What are overdose symptoms? Drowsiness, nausea, rapid heartbeat, tremors, or serotonin syndrome.
Can I drive while taking it? Avoid if it causes drowsiness or impairs focus.
Doctor’s Review
Dr. Ayesha Malik (Psychiatrist, Karachi): “Sert Tablets 50Mg, with sertraline HCl, function as an SSRI to enhance serotonin activity, effectively supporting the management of depression, OCD, and panic disorders.”
Disclaimer
This information is for educational purposes only and is not medical advice, diagnosis, or treatment. Always consult a healthcare professional before starting, stopping, or altering any medication.

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