Loratadine tablets are everywhere in Pakistani allergy clinics, from ENT OPDs at Jinnah Hospital Karachi to general practices in Lahore’s Services Hospital, where docs hand them out for sneezing fits or hives from pollen or dust common in our monsoon shifts. As a second-gen antihistamine, it hits peripheral H1 receptors without crossing into the brain for drowsiness, per PMDC OTC nods for mild allergies. Generics in 10mg tabs cost PKR 50-100 per strip—grab via Servaid or Dawaai.pk—pulled from daily scripts, but doc for kids or combos.
Ingredients
- Active Ingredient: Loratadine 10mg.
- Excipients: Lactose, cornstarch, magnesium stearate—check labels for sensitivities.
Drug Class
Second-Generation H1 Antihistamine.
How It Functions
Loratadine blocks H1 receptors on vessels, airways, gut, and immune cells, cutting histamine-driven itch, sneeze, and swelling without central sedation. In Pakistan’s high-allergen air, it eases symptoms fast, but docs pair with avoidance for chronic cases.
Common Applications
Local allergy guidelines cover:
- Allergic rhinitis (hay fever).
- Conjunctivitis from allergens.
- Chronic idiopathic urticaria (hives).
Dosage Form
Tablets taken orally once daily, with or without food.
Potential Side Effects
Common: Headache, dry mouth.
Others: Tachycardia, hypertension, rash, heavy periods, thirst, pharyngitis, migraine.
Rare from reports: Bronchospasm, dermatitis. ER for severe rash or breathing hits.
Key Warnings and Precautions
PMDC notes:
- Pregnancy: Avoid or doc-guided—Category B.
- Breastfeeding: May drowsy baby—caution.
- Kids: Weight-based dosing; under 2 not routine.
- Grapefruit: Ups levels—skip juice.
No alcohol boost sedation; elderly standard.
When It’s Not Suitable (Contraindications)
Skip if:
- Hypersensitive to loratadine or desloratadine.
Drug Interactions
Flag:
- Grapefruit juice—concentration rise.
- Minimal others, but sedatives may add drowsiness.
In Case of Overdose
Drowsiness, fast heart, headache—doc for support.
Missed Dose
Take soon unless near next; skip, no double.
Storage and Disposal
Room temp (15-30°C), dry, away from light/kids. Pharmacy drop unused.
Quick Tips
- Once daily, evening if needed.
- With water, no crush.
- Hydrate for dry mouth.
Doctor Review
Allergists at AKUH or ENT at PIC prescribe loratadine for seasonal rhinitis where first-gens flop on sleep, starting 10mg adults and 5mg kids under 30kg, but push skin tests and nasal sprays for pollen peaks in Punjab plains.
Laboratory Screening
If persistent:
- Allergy prick/skin tests.
This maps loratadine’s allergy block in Pakistan—quick relief facts, doc doses.
Disclaimer: This is product information only, not a prescription or diagnosis. Consult a qualified Pakistani doctor before using loratadine to ensure it’s safe. Seek immediate care for severe symptoms like breathing trouble or rash.

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