Truglif Met

Introduction

Truglifmet combines two proven diabetes medicines — Empagliflozin and Metformin — into one tablet for adults with Type 2 Diabetes who need extra control over high blood sugar. It’s usually prescribed when metformin alone isn’t cutting it, or when someone is already on both medicines separately and needs a simpler routine. It helps reduce blood sugar without causing weight gain, but it must be used under medical supervision.

Primary Uses

• Type 2 Diabetes management.

• Used when diet + exercise + single therapy are not enough.

• Helps improve both fasting and post-meal glucose levels.

Indications

Doctors prescribe Truglifmet for:

• Patients already using Empagliflozin or Metformin alone with insufficient control.

• Patients switching from separate tablets of both drugs for convenience and better compliance.

How It Works

Two mechanisms working in parallel:

• Metformin reduces glucose production by the liver, improves insulin sensitivity, and slows sugar absorption from food.

• Empagliflozin (SGLT2 inhibitor) blocks kidney glucose reabsorption, forcing excess sugar out through urine.

Together, they control blood sugar from inside the body and via urine excretion.

Side Effects

Common with Empagliflozin:

• Urinary tract infections.

• Genital fungal infections (more common in females).

Common with Metformin:

• Diarrhea or stomach upset.

• Nausea / bloating / indigestion.

• Headache or weakness (rarely).

Seek medical advice if symptoms persist or worsen.

Warnings

Warning 1: Risk of Lactic Acidosis (due to Metformin)
Symptoms may include unexplained fatigue, abdominal pain, difficulty breathing — seek immediate care.

Warning 2: Risk of Low Blood Pressure
Due to fluid loss from Empagliflozin — more likely in kidney patients, elderly, or those on diuretics.

Warning 3: Risk of Ketoacidosis (rare but serious)
If experiencing nausea, vomiting, fast breathing, or abdominal pain — stop medication and get emergency evaluation.

Contraindications

Do not use if:

• You have severe kidney disease or are on dialysis.

• You have metabolic acidosis or diabetic ketoacidosis.

• You are allergic to Empagliflozin or Metformin.

Precautions

• Stay hydrated to avoid dizziness or dehydration.

• Avoid excess alcohol intake — increases lactic acidosis risk.

• Monitor kidney function regularly.

FAQs

Q: Can I take Truglifmet with insulin?
Yes, but insulin dose may need adjustment to avoid low sugar.

Q: Does it cause weight gain?
Generally no — Empagliflozin may even help reduce slight weight.

Q: Can I skip meals while taking it?
No — it increases the risk of hypoglycemia when taken without food.

Q: Is it safe for Type 1 Diabetes?
No — strictly for Type 2 only.

Doctor’s Overview

Dr. Adeel Khan (Endocrinologist):
“Truglifmet is ideal for patients who need dual control. It offers strong sugar reduction with cardiovascular and kidney benefits — but kidney function and hydration must be monitored closely.”

Disclaimer

This is general medical information based on standard prescribing practices in Pakistan. Not a substitute for medical advice. Always consult your doctor before starting or stopping diabetes medication.