Zatofen

Introduction

Zatofen Syrup 60ml is commonly used in Pakistan for allergy-prone children and adults who deal with persistent sneezing, runny nose, or itchy, watery eyes—especially during seasonal pollen bursts or dust exposure. Each spoonful contains Ketotifen, an antihistamine that doesn’t just block histamine reactions but also helps prevent future allergy flare-ups with regular use. It’s slightly sedative, so many parents give it at night to calm allergic irritation and help restless sleep caused by itching or throat irritation.

Primary Uses

Zatofen Syrup is generally used for:

• Allergic rhinitis (sneezing, blocked or runny nose)

• Itchy or watery eyes from seasonal or dust allergies

• Chronic allergic tendencies with repeated episodes

• Can be considered in asthmatic allergy triggers under supervision

How It Works

Ketotifen blocks the effects of histamine, the chemical responsible for itching and inflammation during an allergy attack. It also prevents certain inflammatory substances from activating, which helps in long-term control rather than just quick relief. This dual action makes it more preventive than typical fast-acting antihistamines.

Side Effects

Some users may notice:

• Drowsiness or slowed reactions.

• Agitation or irritability, especially in children.

• Difficulty sleeping (rare paradoxical effect).

• Dry mouth or dizziness.

• Increased appetite or slight weight gain.

• Nausea, vomiting, or stomach upset.

• Burning sensation during urination (cystitis-like symptoms).

Most effects settle once the body adjusts to the medicine.

Drug Interactions

Caution is generally observed when used with:

• Diabetes medications (especially oral antidiabetics).

• Asthma medications.

• Sleeping pills, antidepressants, or anxiety medications.

• Other antihistamines.

• Blood thinners (anticoagulants).

When Not to Use

Avoid Zatofen Syrup if:

• Allergic to Ketotifen.

• History of epilepsy or seizures.

• Currently using oral diabetic medications.

• Breastfeeding.

Precautions & Warnings

• Initial doses may cause drowsiness, so operating vehicles or machinery is usually avoided.

• In epileptic patients, Ketotifen may lower the seizure threshold.

• When taken with oral antidiabetic drugs, low platelet count (thrombocytopenia) has been reported.

• Alcohol increases sedation, so it’s typically avoided alongside.

Doctor’s Overview

Dr. Ayesha Hanif (Pediatric Allergist, Lahore):
“Ketotifen-based syrups like Zatofen are commonly used when allergy symptoms become recurring rather than one-time. It works gradually, so consistency is important. Sedation varies from person to person, so dosing is usually adjusted based on tolerance.”

Storage

• Store at room temperature.

• Keep away from direct sunlight and heat.

• Seal the cap tightly after use to prevent contamination.

Disclaimer: This is a general medical overview for informational purposes based on standard usage in Pakistan. It is not a treatment recommendation. Always consult a healthcare professional for personal medical advice.