Zepres

Introduction

Zepres 5mg Tablets are commonly prescribed in Pakistan for individuals dealing with high blood pressure or weakened heart function. Each tablet contains Enalapril maleate, an ACE inhibitor that relaxes blood vessels to improve blood flow. It’s often used in long-term treatment to reduce the risk of stroke, heart attack, or hospital admissions due to heart failure. The effect usually begins within an hour of intake but may take several weeks of consistent use for full blood pressure stabilization.

Primary Uses

Zepres 5mg is generally used for:

• Hypertension (high blood pressure).

• Heart failure or weakened heart pumping function.

• Prevention of cardiac complications in high-risk patients.

How It Works

Enalapril blocks ACE (angiotensin-converting enzyme) — a substance in the body responsible for tightening blood vessels. By stopping this action, the blood vessels stay relaxed, allowing blood to move with less pressure. This gradually reduces blood pressure and improves heart efficiency.

Side Effects

Some users may notice:

• Headache or dizziness (especially when standing up quickly).

• Shortness of breath or fatigue.

• Diarrhea or stomach discomfort.

• Change in sense of taste.

• Skin rash or swelling of face/lips (allergic reaction).

• High potassium or increased creatinine levels (detected via lab test).

Seek medical attention if facial swelling or breathing difficulty occurs.

When Not to Use

Avoid Zepres if:

• Allergic to Enalapril or other ACE inhibitors.

• History of severe swelling (angioedema).

• Using Aliskiren for blood pressure with diabetes or kidney issues.

Precautions & Warnings

• Low blood pressure may occur initially — lying down and hydration may help.

• If kidney problems exist, potassium levels may rise, so monitoring is required.

• Diabetic users on insulin or oral agents should watch for low blood sugar and high potassium during early treatment.

• Do not stop abruptly, as it may cause rebound blood pressure rise.

Drug Interactions

Use cautiously with:

• ARBs or Aliskiren.

• Potassium supplements or potassium-sparing diuretics.

• Lithium.

• Trimethoprim / Cotrimoxazole.

• Aspirin or Vildagliptin.

• Sacubitril (heart failure medicine).

Doctor’s Overview

Dr. Imran Siddiqui (Cardiologist, Faisalabad):
“Enalapril-based tablets like Zepres are widely used for long-term blood pressure and heart failure management. Regular monitoring of potassium and kidney function ensures safe and effective therapy.”

Storage

• Store at room temperature, away from heat and direct light.

• Keep sealed and out of reach of children.

Disclaimer

This is general information based on standard medical usage and is not a prescription or substitute for clinical advice. Always consult a doctor before starting or adjusting any medication.